Melanoma differentiation-associated gene 5 is critical for protection against theiler's virus-induced demyelinating disease

Keyphrases

• Melanoma Differentiation-associated Gene 5 (MDA5) 100%
• Demyelinating Diseases 100%
• Theiler's Virus 100%
• Cell Infiltration 55%
• Central Nervous System 44%
• Interferon-α (IFN-α) 33%
• Gene-deficient Mice 33%
• Viral Infection 33%
• T Cell Response 22%
• Viral Load 22%
• Glial Cells 22%
• 129SvJ 22%
• Theiler's murine Encephalomyelitis Virus 22%
• Dendritic Cells 11%
• Virus 11%
• Toll-like Receptors 11%
• Interferon Production 11%
• Chemokines 11%
• Gene Activation 11%
• High Viral Load 11%
• Acute Viral Infection 11%
• Clinical Symptoms 11%
• Demyelinating Lesions 11%
• Infiltration Pressure 11%
• Viral Determinants 11%
• Cytokine Genes 11%
• Theiler's murine Encephalomyelitis Virus-induced Demyelinating Disease 11%

Immunology and Microbiology

• Mouse 100%
• Theiler's Murine Encephalomyelitis Virus 100%
• Clinically Isolated Syndrome 100%
• Viral Disease 66%
• Viral Load 50%
• interferon 33%
• Cytokine 33%
• T Cell 33%
• Wild Type 16%
• Interferon Production 16%
• Chemokine 16%
• Interferon Alfa 16%
• Gene Activation 16%

Biochemistry, Genetics and Molecular Biology

• Mouse 100%
• Theiler's Murine Encephalomyelitis Virus 100%
• interferon 50%
• Interferon 50%
• Virus Load 50%
• Cytokine 33%
• T Cell 33%
• Glial Cells 33%
• Eicosanoid Receptor 16%
• Wild Type 16%
• Interferon Production 16%
• Dendritic Cell 16%
• Chemokine 16%
• Gene Activation 16%