@article{7ab4d4a114bd41b7adb11873517e3ef4,
title = "Medical and surgical interventions and outcomes for infants with trisomy 18 (T18) or trisomy 13 (T13) at children{\textquoteright}s hospitals neonatal intensive care units (NICUs)",
abstract = "Objectives: To examine characteristics and outcomes of T18 and T13 infants receiving intensive surgical and medical treatment compared to those receiving non-intensive treatment in NICUs. Study design: Retrospective cohort of infants in the Children{\textquoteright}s Hospitals National Consortium (CHNC) from 2010 to 2016 categorized into three groups by treatment received: surgical, intensive medical, or non-intensive. Results: Among 467 infants admitted, 62% received intensive medical treatment; 27% received surgical treatment. The most common surgery was a gastrostomy tube. Survival in infants who received surgeries was 51%; intensive medical treatment was 30%, and non-intensive treatment was 72%. Infants receiving surgeries spent more time in the NICU and were more likely to receive oxygen and feeding support at discharge. Conclusions: Infants with T13 or T18 at CHNC NICUs represent a select group for whom parents may have desired more intensive treatment. Survival to NICU discharge was possible, and surviving infants had a longer hospital stay and needed more discharge supports.",
author = "{on behalf of the Palliative Care and Ethics Focus Group of the Children{\textquoteright}s Hospital Neonatal Consortium (CHNC)} and Krishna Acharya and Leuthner, {Steven R.} and Isabella Zaniletti and Niehaus, {Jason Z.} and Bishop, {Christine E.} and Coghill, {Carl H.} and Ankur Datta and Narendra Dereddy and Robert DiGeronimo and Laura Jackson and Ling, {Con Yee} and Nana Matoba and Girija Natarajan and Nayak, {Sujir Pritha} and Schlegel, {Amy Brown} and Jamie Seale and Anita Shah and Julie Weiner and Williams, {Helen O.} and Wojcik, {Monica H.} and Fry, {Jessica T.} and Kevin Sullivan and Anthony Piazza and Gregory Sysyn and Carl Coghill and Ajay Talati and Anne Hansen and Tanzeema Houssain and Karna Murthy and Gustave Falciglia and Beth Haberman and Kristina Reber and Rashmin Savani and Theresa Grover and Girija Natarajan and Annie Chi and Yvette Johnson and Gautham Suresh and William Engle and Eugenia Pallotto and Robert Lyle and Becky Rogers and Rachel Chapman and Jamie Limjoco and Priscilla Joe and Jacquelyn Evans and Michael Padula and Beverly Brozanski and Rakesh Rao and Amit Mathur",
note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer Nature America, Inc.",
year = "2021",
month = jul,
doi = "10.1038/s41372-021-01111-9",
language = "English",
volume = "41",
pages = "1745--1754",
journal = "Journal of Perinatology",
issn = "0743-8346",
number = "7",
}