Die mechanochemische Kopplung in der Hörzelle benötigt ein intaktes Zytoskelett

Translated title of the contribution: Mechano-chemical coupling in hearing requires an intact cytoskeleton

H. P. Zenner, N. Wegner, R. Thalmann

Research output: Contribution to journalArticle

Abstract

Monospecific antibodies to actin and to tubulin were used as immunofluorescent and ferritin-labelled probes to evaluate the distribution of microtubules and actin filaments in the hearing organs from mouse, guinea pig and fish. The results indicate that in cochlear receptor cells actin and actin filaments as well as tubulin and microtubules are integral cytoskeletal elements. The presence of actin suggests a possible contractile mechanism within the sensory cilia whereas tubulin is thought to play an important role in the stability of sensory cells. Both proteins are discussed to form structural elements required for the mechano-chemical coupling in hearing.

Translated title of the contributionMechano-chemical coupling in hearing requires an intact cytoskeleton
Original languageGerman
Number of pages1
JournalArchives of Oto-Rhino-Laryngology
Volume231
Issue number2-3
DOIs
StatePublished - Jan 1 1981

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