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Mechanistic insights into volatile anesthetic modulation of k2p channels
Aboubacar Wague
, Thomas T. Joseph
, Kellie A. Woll
, Weiming Bu
, Kiran A. Vaidya
, Natarajan V. Bhanu
,
Benjamin A. Garcia
, Crina M. Nimigean
, Roderic G. Eckenhoff
, Paul M. Riegelhaupt
School of Medicine
Department of Biochemistry & Molecular Biophysics
Siteman Cancer Center
Center for Drug Discovery
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Brain Tumor Center
DBBS - Biochemistry, Biophysics, and Structural Biology
Research output
:
Contribution to journal
›
Article
›
peer-review
21
Scopus citations
Overview
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Keyphrases
Mechanistic Insight
100%
Volatile Anesthetics
100%
K2P Channel
100%
Binding Site
12%
Molecular Dynamics Simulation
12%
Clinically Significant
12%
Channel Activity
12%
Mutagenesis
12%
Binding Region
12%
Anesthetics
12%
Potassium Channel
12%
Anesthetic Drugs
12%
Isoflurane
12%
General Anesthesia
12%
Photoaffinity
12%
Functional Importance
12%
Neighboring Residues
12%
Mechanical Stretch
12%
Pharmacological Modulators
12%
Biochemical Modification
12%
Anesthetic Sensitivity
12%
Molecular Contacts
12%
Biochemistry, Genetics and Molecular Biology
Binding Site
100%
Mutagenesis
100%
Potassium Channel
100%
Isoflurane
100%
Medicine and Dentistry
Inhalation Anesthetic Agent
100%
Potassium Channel
12%
Binding Site
12%
Mutagenesis
12%
General Anesthesia
12%
Isoflurane
12%
Pharmacology, Toxicology and Pharmaceutical Science
Inhalation Anesthetic Agent
100%
Potassium Channel
12%
Binding Site
12%
Isoflurane
12%
Mutagenesis
12%