Mechanisms of Zika Virus Infection and Neuropathogenesis

David Olagnier, Michela Muscolini, Carolyn B. Coyne, Michael S. Diamond, John Hiscott

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


A spotlight has been focused on the mosquito-borne Zika virus (ZIKV) because of its epidemic outbreak in Brazil and Latin America, as well as the severe neurological manifestations of microcephaly and Guillain-Barré syndrome associated with infection. In this review, we discuss the recent literature on ZIKV-host interactions, including new mechanistic insight concerning the basis of ZIKV-induced neuropathogenesis.

Original languageEnglish
Pages (from-to)367-372
Number of pages6
JournalDNA and cell biology
Issue number8
StatePublished - Aug 2016


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