TY - JOUR
T1 - Mechanisms of Zika Virus Infection and Neuropathogenesis
AU - Olagnier, David
AU - Muscolini, Michela
AU - Coyne, Carolyn B.
AU - Diamond, Michael S.
AU - Hiscott, John
N1 - Funding Information:
Acknowledgments This research was supported by grants from the NIH (AI108861), the Italian Association for Cancer Research, and the Pasteur GPF Vaccinology program to J.H.; by grants from the Burroughs Wellcome Fund and NIH (R01 AI073755) to M.S.D.; and from the Burroughs Wellcome Fund and NIH (R01 AI081759 and HD075665) to C.B.C.; D.O. was supported by a Peter Quinlan McGill postdoctoral fellowship. The authors acknowledge all the contributions in the field that could not be included in the review.
Publisher Copyright:
© Copyright 2016, Mary Ann Liebert, Inc. 2016.
PY - 2016/8
Y1 - 2016/8
N2 - A spotlight has been focused on the mosquito-borne Zika virus (ZIKV) because of its epidemic outbreak in Brazil and Latin America, as well as the severe neurological manifestations of microcephaly and Guillain-Barré syndrome associated with infection. In this review, we discuss the recent literature on ZIKV-host interactions, including new mechanistic insight concerning the basis of ZIKV-induced neuropathogenesis.
AB - A spotlight has been focused on the mosquito-borne Zika virus (ZIKV) because of its epidemic outbreak in Brazil and Latin America, as well as the severe neurological manifestations of microcephaly and Guillain-Barré syndrome associated with infection. In this review, we discuss the recent literature on ZIKV-host interactions, including new mechanistic insight concerning the basis of ZIKV-induced neuropathogenesis.
UR - http://www.scopus.com/inward/record.url?scp=84986200978&partnerID=8YFLogxK
U2 - 10.1089/dna.2016.3404
DO - 10.1089/dna.2016.3404
M3 - Article
C2 - 27348136
AN - SCOPUS:84986200978
SN - 1044-5498
VL - 35
SP - 367
EP - 372
JO - DNA and cell biology
JF - DNA and cell biology
IS - 8
ER -