Mechanisms of blindness: Animal models provide insight into distinct CRX-associated retinopathies

Keyphrases

• DNA Binding 100%
• Retinopathy 100%
• Blindness 100%
• Pathogenic Mechanism 100%
• Leber Congenital Amaurosis 75%
• Missense mutation 50%
• CRX Gene 50%
• Gene Expression 25%
• Mutant Protein 25%
• Hypomorphic mutation 25%
• Novel Therapeutics 25%
• Frameshift 25%
• Molecular Behavior 25%
• Photoreceptor 25%
• Associated Diseases 25%
• Disease Class 25%
• Frameshift mutation 25%
• Cause of Disease 25%
• Retinitis pigmentosa 25%
• Nonsense mutation 25%
• Genotype-phenotype Correlation 25%
• Animal Disease Models 25%
• In Vivo Assessment 25%
• Homeodomain Transcription Factor 25%
• Mutation Type 25%
• Mammalian Models 25%
• Intact DNA 25%
• Disease Correlation 25%
• Cone-rod Dystrophy 25%
• Inherited Retinopathy 25%
• Retinal Phenotype 25%

Biochemistry, Genetics and Molecular Biology

• Animal Model 100%
• DNA Binding 100%
• Leber's Congenital Amaurosis 75%
• Missense Mutation 50%
• Gene Expression 25%
• Mutant Protein 25%
• Transcription Factors 25%
• Synapsin I 25%
• Homeodomain 25%
• Frameshift Mutation 25%
• Retinitis pigmentosa 25%
• Nonsense Mutation 25%
• Genotype Phenotype Correlation 25%
• Mammalian Model 25%
• Animal Disease Model 25%
• CRX (Gene) 25%