Abstract

The mechanical function of matrix synthesized by intervertebral disc (IVD) cells in alginate was examined by measuring material properties in both compression and shear testing of configurations. Samples were evaluated for mechanical function after 1, 4, 8, and 16 weeks in culture. The main results is that while IVD cells exhibit significant biosynthetic activity at both transcriptional and translational stages when cultured in alginate, they are not able to form a functional matrix.

Original languageEnglish
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
PublisherASME
Pages119-120
Number of pages2
Volume42
ISBN (Print)0791816117
StatePublished - 1999
Event1999 Bioengineering Conference - Big Sky, MT, USA
Duration: Jun 16 1999Jun 20 1999

Conference

Conference1999 Bioengineering Conference
CityBig Sky, MT, USA
Period06/16/9906/20/99

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