Mechanical properties of dilated human ascending aorta

Ruth J. Okamoto; Jessica E. Wagenseil; William R. DeLong; Sara J. Peterson; Nicholas T. Kouchoukos; Thoralf M. Sundt

doi:10.1114/1.1484220

Mechanical properties of dilated human ascending aorta

Ruth J. Okamoto, Jessica E. Wagenseil, William R. DeLong, Sara J. Peterson, Nicholas T. Kouchoukos, Thoralf M. Sundt

Research output: Contribution to journal › Article › peer-review

111 Scopus citations

Abstract

Mechanical properties for dilated human ascending aorta obtained from excised surgical tissue were presented. Specimens for opening angle, biaxial elastic, and uniaxial circumferential strength tests were cut from excised tissue obtained from 54 patients (aged 18-81 years) undergoing elective aortic graft replacement surgery. Results indicated rapid increase in circumferential and axial stresses at lower strains in the older patient group than in younger. Changes in mechanical properties suggested that age influenced the risk of aortic dissection or rupture of dilated ascending aorta.

Original language	English
Pages (from-to)	624-635
Number of pages	12
Journal	Annals of biomedical engineering
Volume	30
Issue number	5
DOIs	https://doi.org/10.1114/1.1484220
State	Published - 2002

Keywords

Aortic disease
Elasticity
Strength
Vascular mechanics

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title = "Mechanical properties of dilated human ascending aorta",

abstract = "Mechanical properties for dilated human ascending aorta obtained from excised surgical tissue were presented. Specimens for opening angle, biaxial elastic, and uniaxial circumferential strength tests were cut from excised tissue obtained from 54 patients (aged 18-81 years) undergoing elective aortic graft replacement surgery. Results indicated rapid increase in circumferential and axial stresses at lower strains in the older patient group than in younger. Changes in mechanical properties suggested that age influenced the risk of aortic dissection or rupture of dilated ascending aorta.",

keywords = "Aortic disease, Elasticity, Strength, Vascular mechanics",

author = "Okamoto, {Ruth J.} and Wagenseil, {Jessica E.} and DeLong, {William R.} and Peterson, {Sara J.} and Kouchoukos, {Nicholas T.} and Sundt, {Thoralf M.}",

note = "Funding Information: This research was supported by grants from the Whi-taker Foundation (R. J. O.) and the National Marfan Foundation and a Whitaker Graduate Fellowship (J. E.",

year = "2002",

doi = "10.1114/1.1484220",

language = "English",

volume = "30",

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T1 - Mechanical properties of dilated human ascending aorta

AU - Okamoto, Ruth J.

AU - Wagenseil, Jessica E.

AU - DeLong, William R.

AU - Peterson, Sara J.

AU - Kouchoukos, Nicholas T.

AU - Sundt, Thoralf M.

N1 - Funding Information: This research was supported by grants from the Whi-taker Foundation (R. J. O.) and the National Marfan Foundation and a Whitaker Graduate Fellowship (J. E.

PY - 2002

Y1 - 2002

N2 - Mechanical properties for dilated human ascending aorta obtained from excised surgical tissue were presented. Specimens for opening angle, biaxial elastic, and uniaxial circumferential strength tests were cut from excised tissue obtained from 54 patients (aged 18-81 years) undergoing elective aortic graft replacement surgery. Results indicated rapid increase in circumferential and axial stresses at lower strains in the older patient group than in younger. Changes in mechanical properties suggested that age influenced the risk of aortic dissection or rupture of dilated ascending aorta.

AB - Mechanical properties for dilated human ascending aorta obtained from excised surgical tissue were presented. Specimens for opening angle, biaxial elastic, and uniaxial circumferential strength tests were cut from excised tissue obtained from 54 patients (aged 18-81 years) undergoing elective aortic graft replacement surgery. Results indicated rapid increase in circumferential and axial stresses at lower strains in the older patient group than in younger. Changes in mechanical properties suggested that age influenced the risk of aortic dissection or rupture of dilated ascending aorta.

KW - Aortic disease

KW - Elasticity

KW - Strength

KW - Vascular mechanics

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DO - 10.1114/1.1484220

M3 - Article

C2 - 12108837

AN - SCOPUS:0035990846

SN - 0090-6964

VL - 30

SP - 624

EP - 635

JO - Annals of Biomedical Engineering

JF - Annals of Biomedical Engineering

IS - 5

ER -

Mechanical properties of dilated human ascending aorta

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Keywords

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