Mechanical properties of dilated human ascending aorta

Ruth J. Okamoto, Jessica E. Wagenseil, William R. DeLong, Sara J. Peterson, Nicholas T. Kouchoukos, Thoralf M. Sundt

Research output: Contribution to journalArticlepeer-review

111 Scopus citations


Mechanical properties for dilated human ascending aorta obtained from excised surgical tissue were presented. Specimens for opening angle, biaxial elastic, and uniaxial circumferential strength tests were cut from excised tissue obtained from 54 patients (aged 18-81 years) undergoing elective aortic graft replacement surgery. Results indicated rapid increase in circumferential and axial stresses at lower strains in the older patient group than in younger. Changes in mechanical properties suggested that age influenced the risk of aortic dissection or rupture of dilated ascending aorta.

Original languageEnglish
Pages (from-to)624-635
Number of pages12
JournalAnnals of biomedical engineering
Issue number5
StatePublished - 2002


  • Aortic disease
  • Elasticity
  • Strength
  • Vascular mechanics


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