Mechanical behavior and matrisome gene expression in the aneurysm-prone thoracic aorta of newborn lysyl oxidase knockout mice

Keyphrases

• Knock-in Mouse Model 100%
• Gene Expression 100%
• Aneurysm 100%
• Thoracic Aorta 100%
• Lysyl Oxidase 100%
• Mechanical Behavior 100%
• Matrisome 100%
• Ascending Aorta 33%
• Descending Aorta 27%
• Smooth muscle Cells 22%
• Elastin 16%
• Gene Set 16%
• Thoracic Aortic Aneurysm 16%
• Location-specific 16%
• Collagen 11%
• Extracellular Matrix 11%
• Gene Set Enrichment Analysis 11%
• Differential Expression 11%
• Collagen Cross-linking 11%
• Secreted Factors 11%
• Thoracic Aortic Dissection 11%
• Cell-to-cell 5%
• Genotype 5%
• Associated Proteins 5%
• Aorta 5%
• Expression Level 5%
• Fluorescence Microscopy 5%
• Matrix-based 5%
• Gene-specific 5%
• Wall Thickness 5%
• Matrix Remodeling 5%
• Aortic Wall 5%
• Regulatory Genes 5%
• Tangent Modulus 5%
• Microarchitecture 5%
• Outer Diameter 5%
• Structural Matrix 5%
• Specific Difference 5%
• Elastic Lamina 5%
• Cell Cycle Genes 5%
• Extracellular Matrix Glycoprotein 5%
• Outer Wall 5%
• Pressure Myography 5%
• Circumferential Stress 5%
• Circumferential Stretch 5%
• Stretch Ratio 5%
• Opening Angle 5%
• Chemo-mechanical 5%

Biochemistry, Genetics and Molecular Biology

• Knockout Mouse 100%
• Gene Expression 100%
• Lysyl Oxidase 100%
• Cross-Link 16%
• Elastin 16%
• Upregulation 11%
• Genome-Wide Analysis of Gene Expression 11%
• Cell Cycle 5%
• Glycoprotein 5%
• Fluorescence Microscopy 5%
• Extracellular Matrix Proteins 5%
• Scleroprotein 5%
• Genotyping 5%
• Locus Control Region 5%