TY - JOUR
T1 - Measuring participation in individuals with Parkinson disease
T2 - Relationships with disease severity, quality of life, and mobility
AU - Duncan, Ryan P.
AU - Earhart, Gammon M.
N1 - Funding Information:
The authors thank John Michael Rotello and Joshua Funk for their assistance in data entry and Abi Leddy for her assistance with data collection. This study was funded by a grant from the Parkinson’s Disease Foundation. The authors have no commercial or financial interests related to this work. The study sponsors played no role in the study design, collection, analysis and interpretation of data, the writing of the manuscript, the final conclusions drawn or the decision to submit the manuscript for publication.
PY - 2011
Y1 - 2011
N2 - Purpose. Our aims were to: (1) describe participation in people with Parkinson disease (PD), (2) evaluate the relationship between quality of life and participation and (3) determine the mobliity measures which are predictive of participation. Methods. Participants with idiopathic PD (n=62) were tested off medication for participation (Activity Card Sort), quality of life (PDQ-39), disease severity (MDS-UPDRS) and mobility (Berg Balance Scale, Five Time Sit to Stand (FTSTS), Six Minute Walk, forward walking velocity, dual-task walking velocity and Freezing of Gait Questionnaire (FOGQ)). Relationships of all variables to participation were examined using Pearson correlations. Subsequent regression analysis was employed to determine the mobility measures which best predicted the participation. Results. Participants with PD retained, on average, 78.3% (SD=15.6%) of total activities. Participation was negatively correlated with all PDQ-39 domains (r range -0.36 to -0.78, all p<0.005) with the mobility domain having the strongest correlation. All mobility measures were significantly correlated with participation, with the final regression model including only FTSTS and FOGQ which combined explained 37% of the variance in participation. Conclusions. Participation is highly related to mobility-related QOL and may be most impacted by ability to stand up from a chair and freezing of gait in those with PD.
AB - Purpose. Our aims were to: (1) describe participation in people with Parkinson disease (PD), (2) evaluate the relationship between quality of life and participation and (3) determine the mobliity measures which are predictive of participation. Methods. Participants with idiopathic PD (n=62) were tested off medication for participation (Activity Card Sort), quality of life (PDQ-39), disease severity (MDS-UPDRS) and mobility (Berg Balance Scale, Five Time Sit to Stand (FTSTS), Six Minute Walk, forward walking velocity, dual-task walking velocity and Freezing of Gait Questionnaire (FOGQ)). Relationships of all variables to participation were examined using Pearson correlations. Subsequent regression analysis was employed to determine the mobility measures which best predicted the participation. Results. Participants with PD retained, on average, 78.3% (SD=15.6%) of total activities. Participation was negatively correlated with all PDQ-39 domains (r range -0.36 to -0.78, all p<0.005) with the mobility domain having the strongest correlation. All mobility measures were significantly correlated with participation, with the final regression model including only FTSTS and FOGQ which combined explained 37% of the variance in participation. Conclusions. Participation is highly related to mobility-related QOL and may be most impacted by ability to stand up from a chair and freezing of gait in those with PD.
KW - Parkinson disease
KW - participation
KW - quality of life
UR - http://www.scopus.com/inward/record.url?scp=79959399156&partnerID=8YFLogxK
U2 - 10.3109/09638288.2010.533245
DO - 10.3109/09638288.2010.533245
M3 - Article
C2 - 21091047
AN - SCOPUS:79959399156
VL - 33
SP - 1440
EP - 1446
JO - Disability and Rehabilitation
JF - Disability and Rehabilitation
SN - 0963-8288
IS - 15-16
ER -