Abstract
In the present study, we determined whether exposure of mammalian cells to 3.2-5.1 W/kg specific absorption rate (SAR) radiofrequency fields could induce DNA damage in murine C3H 10T1/2 fibroblasts. Cell cultures were exposed to 847.74 MHz code-division multiple access (CDMA) and 835.62 frequency-division multiple access (FDMA) modulated radiations in radial transmission line (RTL) irradiators in which the temperature was regulated to 37.0 ± 0.3°C. Using the alkaline comet assay to measure DNA damage, we found no statistically significant differences in either comet moment or comet length between sham-exposed cells and those exposed for 2, 4 or 24 h to CDMA or FDMA radiations in either exponentially growing or plateau-phase cells. Further, a 4-h incubation after the 2-h exposure resulted in no significant changes in comet moment or comet length. Our results show that exposure of cultured C3H 10T1/2 cells at 37°C CDMA or FDMA at SAR values of up to 5.1 W/kg did not induce measurable DNA damage.
Original language | English |
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Pages (from-to) | 328-332 |
Number of pages | 5 |
Journal | Radiation research |
Volume | 156 |
Issue number | 3 |
DOIs | |
State | Published - 2001 |