TY - CHAP
T1 - Mathematical Modeling of Cell Migration
AU - Carlsson, Anders E.
AU - Sept, David
N1 - Funding Information:
We thank many of the people cited in this work for sharing their data and figures with us. We further thank John Cooper for many stimulating discussions and a critical reading of the manuscript. This work was supported by grants DMS‐0240770 from the National Science Foundation (AEC) and GM‐067246 from the National Institutes of Health (DS).
PY - 2008
Y1 - 2008
N2 - Mathematical modeling has become increasingly important in many areas of biology during the past two decades, and the area of cell migration and motility has seen significant contributions from a wide range of modeling approaches. In this chapter, we cover examples from the broad range of work in this area, emphasizing the models' biological significance and the relationships between them. We focus on three specific areas: cell protrusion, cell adhesion, and retraction/whole-cell models. At the end of this chapter, we provide our perspective on issues that future models and experiments should consider in order to advance the boundaries of this field.
AB - Mathematical modeling has become increasingly important in many areas of biology during the past two decades, and the area of cell migration and motility has seen significant contributions from a wide range of modeling approaches. In this chapter, we cover examples from the broad range of work in this area, emphasizing the models' biological significance and the relationships between them. We focus on three specific areas: cell protrusion, cell adhesion, and retraction/whole-cell models. At the end of this chapter, we provide our perspective on issues that future models and experiments should consider in order to advance the boundaries of this field.
UR - http://www.scopus.com/inward/record.url?scp=35448981763&partnerID=8YFLogxK
U2 - 10.1016/S0091-679X(07)84029-5
DO - 10.1016/S0091-679X(07)84029-5
M3 - Chapter
C2 - 17964954
AN - SCOPUS:35448981763
SN - 0123725208
SN - 9780123725202
T3 - Methods in Cell Biology
SP - 911
EP - 937
BT - Biophysical Tools for Biologists, Volume One
A2 - Correi, John
A2 - Detrich, III, William
ER -