Maternal Stroke: A Call for Action

Islam Y. Elgendy, Syed Bukhari, Amr F. Barakat, Carl J. Pepine, Kathryn J. Lindley, Eliza C. Miller

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations

Abstract

Maternal mortality rates have been steadily increasing in the United States, and cardiovascular mortality is the leading cause of death among pregnant and postpartum women. Maternal stroke accounts for a significant burden of cardiovascular mortality. Data suggest that rates of maternal stroke have been increasing in recent years. Advancing maternal age at the time of birth and the increasing prevalence of traditional cardiovascular risk factors, and other risk factors, as well, such as hypertensive disorders of pregnancy, migraine, and infections, may contribute to increased rates of maternal stroke. In this article, we provide an overview of the epidemiology of maternal stroke, explore mechanisms that may explain increasing rates of stroke among pregnant women, and identify key knowledge gaps for future investigation in this area.

Original languageEnglish
Pages (from-to)727-738
Number of pages12
JournalCirculation
Volume143
Issue number7
DOIs
StatePublished - Feb 16 2021

Keywords

  • cerebral hemorrhage
  • hemorrhagic stroke
  • ischemic stroke
  • postpartum period
  • pre-eclampsia
  • pregnancy
  • subarachnoid hemorrhage

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