Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium

Ravi P. Kiran; Gursimran S. Kochhar; Revital Kariv; Douglas K. Rex; Akira Sugita; David T. Rubin; Udayakumar Navaneethan; Tracy L. Hull; Huaibin Mabel Ko; Xiuli Liu; Lisa A. Kachnic; Scott Strong; Marietta Iacucci; Willem Bemelman; Philip Fleshner; Rachael A. Safyan; Paulo G. Kotze; André D'Hoore; Omar Faiz; Simon Lo; Jean H. Ashburn; Antonino Spinelli; Charles N. Bernstein; Sunanda V. Kane; Raymond K. Cross; Jason Schairer; James T. McCormick; Francis A. Farraye; Shannon Chang; Ellen J. Scherl; David A. Schwartz; David H. Bruining; Jessica Philpott; Stuart Bentley-Hibbert; Dino Tarabar; Sandra El-Hachem; William J. Sandborn; Mark S. Silverberg; Darrell S. Pardi; James M. Church; Bo Shen

doi:10.1016/S2468-1253(22)00039-5

Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium

Ravi P. Kiran, Gursimran S. Kochhar, Revital Kariv, Douglas K. Rex, Akira Sugita, David T. Rubin, Udayakumar Navaneethan, Tracy L. Hull, Huaibin Mabel Ko, Xiuli Liu, Lisa A. Kachnic, Scott Strong, Marietta Iacucci, Willem Bemelman, Philip Fleshner, Rachael A. Safyan, Paulo G. Kotze, André D'Hoore, Omar Faiz, Simon LoJean H. Ashburn, Antonino Spinelli, Charles N. Bernstein, Sunanda V. Kane, Raymond K. Cross, Jason Schairer, James T. McCormick, Francis A. Farraye, Shannon Chang, Ellen J. Scherl, David A. Schwartz, David H. Bruining, Jessica Philpott, Stuart Bentley-Hibbert, Dino Tarabar, Sandra El-Hachem, William J. Sandborn, Mark S. Silverberg, Darrell S. Pardi, James M. Church, Bo Shen

Division of Anatomic and Molecular Pathology (AMP)

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

Surveillance pouchoscopy is recommended for patients with restorative proctocolectomy with ileal pouch–anal anastomosis in ulcerative colitis or familial adenomatous polyposis, with the surveillance interval depending on the risk of neoplasia. Neoplasia in patients with ileal pouches mainly have a glandular source and less often are of squamous cell origin. Various grades of neoplasia can occur in the prepouch ileum, pouch body, rectal cuff, anal transition zone, anus, or perianal skin. The main treatment modalities are endoscopic polypectomy, endoscopic ablation, endoscopic mucosal resection, endoscopic submucosal dissection, surgical local excision, surgical circumferential resection and re-anastomosis, and pouch excision. The choice of the treatment modality is determined by the grade, location, size, and features of neoplastic lesions, along with patients' risk of neoplasia and comorbidities, and local endoscopic and surgical expertise.

Original language	English
Pages (from-to)	871-893
Number of pages	23
Journal	The Lancet Gastroenterology and Hepatology
Volume	7
Issue number	9
DOIs	https://doi.org/10.1016/S2468-1253(22)00039-5
State	Published - Sep 2022

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Kiran, R. P., Kochhar, G. S., Kariv, R., Rex, D. K., Sugita, A., Rubin, D. T., Navaneethan, U., Hull, T. L., Ko, H. M., Liu, X., Kachnic, L. A., Strong, S., Iacucci, M., Bemelman, W., Fleshner, P., Safyan, R. A., Kotze, P. G., D'Hoore, A., Faiz, O., ... Shen, B. (2022). Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium. The Lancet Gastroenterology and Hepatology, 7(9), 871-893. https://doi.org/10.1016/S2468-1253(22)00039-5

@article{facdf2e1cd144f05ab0331b56c1cfbdf,

title = "Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium",

abstract = "Surveillance pouchoscopy is recommended for patients with restorative proctocolectomy with ileal pouch–anal anastomosis in ulcerative colitis or familial adenomatous polyposis, with the surveillance interval depending on the risk of neoplasia. Neoplasia in patients with ileal pouches mainly have a glandular source and less often are of squamous cell origin. Various grades of neoplasia can occur in the prepouch ileum, pouch body, rectal cuff, anal transition zone, anus, or perianal skin. The main treatment modalities are endoscopic polypectomy, endoscopic ablation, endoscopic mucosal resection, endoscopic submucosal dissection, surgical local excision, surgical circumferential resection and re-anastomosis, and pouch excision. The choice of the treatment modality is determined by the grade, location, size, and features of neoplastic lesions, along with patients' risk of neoplasia and comorbidities, and local endoscopic and surgical expertise.",

author = "Kiran, {Ravi P.} and Kochhar, {Gursimran S.} and Revital Kariv and Rex, {Douglas K.} and Akira Sugita and Rubin, {David T.} and Udayakumar Navaneethan and Hull, {Tracy L.} and Ko, {Huaibin Mabel} and Xiuli Liu and Kachnic, {Lisa A.} and Scott Strong and Marietta Iacucci and Willem Bemelman and Philip Fleshner and Safyan, {Rachael A.} and Kotze, {Paulo G.} and Andr{\'e} D'Hoore and Omar Faiz and Simon Lo and Ashburn, {Jean H.} and Antonino Spinelli and Bernstein, {Charles N.} and Kane, {Sunanda V.} and Cross, {Raymond K.} and Jason Schairer and McCormick, {James T.} and Farraye, {Francis A.} and Shannon Chang and Scherl, {Ellen J.} and Schwartz, {David A.} and Bruining, {David H.} and Jessica Philpott and Stuart Bentley-Hibbert and Dino Tarabar and Sandra El-Hachem and Sandborn, {William J.} and Silverberg, {Mark S.} and Pardi, {Darrell S.} and Church, {James M.} and Bo Shen",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Ltd",

year = "2022",

month = sep,

doi = "10.1016/S2468-1253(22)00039-5",

language = "English",

volume = "7",

pages = "871--893",

journal = "The Lancet Gastroenterology and Hepatology",

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Kiran, RP, Kochhar, GS, Kariv, R, Rex, DK, Sugita, A, Rubin, DT, Navaneethan, U, Hull, TL, Ko, HM, Liu, X, Kachnic, LA, Strong, S, Iacucci, M, Bemelman, W, Fleshner, P, Safyan, RA, Kotze, PG, D'Hoore, A, Faiz, O, Lo, S, Ashburn, JH, Spinelli, A, Bernstein, CN, Kane, SV, Cross, RK, Schairer, J, McCormick, JT, Farraye, FA, Chang, S, Scherl, EJ, Schwartz, DA, Bruining, DH, Philpott, J, Bentley-Hibbert, S, Tarabar, D, El-Hachem, S, Sandborn, WJ, Silverberg, MS, Pardi, DS, Church, JM & Shen, B 2022, 'Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium', The Lancet Gastroenterology and Hepatology, vol. 7, no. 9, pp. 871-893. https://doi.org/10.1016/S2468-1253(22)00039-5

TY - JOUR

T1 - Management of pouch neoplasia

T2 - consensus guidelines from the International Ileal Pouch Consortium

AU - Kiran, Ravi P.

AU - Kochhar, Gursimran S.

AU - Kariv, Revital

AU - Rex, Douglas K.

AU - Sugita, Akira

AU - Rubin, David T.

AU - Navaneethan, Udayakumar

AU - Hull, Tracy L.

AU - Ko, Huaibin Mabel

AU - Liu, Xiuli

AU - Kachnic, Lisa A.

AU - Strong, Scott

AU - Iacucci, Marietta

AU - Bemelman, Willem

AU - Fleshner, Philip

AU - Safyan, Rachael A.

AU - Kotze, Paulo G.

AU - D'Hoore, André

AU - Faiz, Omar

AU - Lo, Simon

AU - Ashburn, Jean H.

AU - Spinelli, Antonino

AU - Bernstein, Charles N.

AU - Kane, Sunanda V.

AU - Cross, Raymond K.

AU - Schairer, Jason

AU - McCormick, James T.

AU - Farraye, Francis A.

AU - Chang, Shannon

AU - Scherl, Ellen J.

AU - Schwartz, David A.

AU - Bruining, David H.

AU - Philpott, Jessica

AU - Bentley-Hibbert, Stuart

AU - Tarabar, Dino

AU - El-Hachem, Sandra

AU - Sandborn, William J.

AU - Silverberg, Mark S.

AU - Pardi, Darrell S.

AU - Church, James M.

AU - Shen, Bo

PY - 2022/9

Y1 - 2022/9

N2 - Surveillance pouchoscopy is recommended for patients with restorative proctocolectomy with ileal pouch–anal anastomosis in ulcerative colitis or familial adenomatous polyposis, with the surveillance interval depending on the risk of neoplasia. Neoplasia in patients with ileal pouches mainly have a glandular source and less often are of squamous cell origin. Various grades of neoplasia can occur in the prepouch ileum, pouch body, rectal cuff, anal transition zone, anus, or perianal skin. The main treatment modalities are endoscopic polypectomy, endoscopic ablation, endoscopic mucosal resection, endoscopic submucosal dissection, surgical local excision, surgical circumferential resection and re-anastomosis, and pouch excision. The choice of the treatment modality is determined by the grade, location, size, and features of neoplastic lesions, along with patients' risk of neoplasia and comorbidities, and local endoscopic and surgical expertise.

AB - Surveillance pouchoscopy is recommended for patients with restorative proctocolectomy with ileal pouch–anal anastomosis in ulcerative colitis or familial adenomatous polyposis, with the surveillance interval depending on the risk of neoplasia. Neoplasia in patients with ileal pouches mainly have a glandular source and less often are of squamous cell origin. Various grades of neoplasia can occur in the prepouch ileum, pouch body, rectal cuff, anal transition zone, anus, or perianal skin. The main treatment modalities are endoscopic polypectomy, endoscopic ablation, endoscopic mucosal resection, endoscopic submucosal dissection, surgical local excision, surgical circumferential resection and re-anastomosis, and pouch excision. The choice of the treatment modality is determined by the grade, location, size, and features of neoplastic lesions, along with patients' risk of neoplasia and comorbidities, and local endoscopic and surgical expertise.

UR - http://www.scopus.com/inward/record.url?scp=85135495232&partnerID=8YFLogxK

U2 - 10.1016/S2468-1253(22)00039-5

DO - 10.1016/S2468-1253(22)00039-5

M3 - Review article

C2 - 35798022

AN - SCOPUS:85135495232

SN - 2468-1253

VL - 7

SP - 871

EP - 893

JO - The Lancet Gastroenterology and Hepatology

JF - The Lancet Gastroenterology and Hepatology

IS - 9

ER -

Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium

Abstract

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