TY - JOUR
T1 - Management of optic neuritis and multiple sclerosis
AU - Van Stavern, Gregory P.
PY - 2001/12/27
Y1 - 2001/12/27
N2 - Optic neuritis and multiple sclerosis (MS) are common causes of visual and neurologic dysfunction in young adults. Advances in magnetic resonance imaging, molecular genetics, and neuroimmunology have increased our understanding of the pathophysiology underlying both disorders. Corticosteroids remain the mainstay of treatment of optic neuritis, but alternate dosages and routes of administration are undergoing investigation. The available therapies for MS have expanded, and there is evidence that early intervention is beneficial. Treatments for MS show sustained efficacy, but are not curative, and adjunctive treatments may prove valuable in patients with progressive visual and neurologic disability.
AB - Optic neuritis and multiple sclerosis (MS) are common causes of visual and neurologic dysfunction in young adults. Advances in magnetic resonance imaging, molecular genetics, and neuroimmunology have increased our understanding of the pathophysiology underlying both disorders. Corticosteroids remain the mainstay of treatment of optic neuritis, but alternate dosages and routes of administration are undergoing investigation. The available therapies for MS have expanded, and there is evidence that early intervention is beneficial. Treatments for MS show sustained efficacy, but are not curative, and adjunctive treatments may prove valuable in patients with progressive visual and neurologic disability.
UR - http://www.scopus.com/inward/record.url?scp=0035208255&partnerID=8YFLogxK
U2 - 10.1097/00055735-200112000-00004
DO - 10.1097/00055735-200112000-00004
M3 - Review article
C2 - 11734679
AN - SCOPUS:0035208255
SN - 1040-8738
VL - 12
SP - 400
EP - 407
JO - Current Opinion in Ophthalmology
JF - Current Opinion in Ophthalmology
IS - 6
ER -