TY - JOUR
T1 - Management of localized extremity and retroperitoneal soft tissue sarcoma
AU - Abaricia, Sarah
AU - Van Tine, Brian Andrew
N1 - Funding Information:
BAVT reports Basic Science Grant Funding from Pfizer not relating to this work; Basic Science Grant Funding from Pfizer, Tracon and Merck; consulting fees from Epizyme, Lilly, CytRX, Janssen, Immune Design, Daiichi Sankyo, Plexxicon and Adaptimmune; and speaking fees from Caris, Janseen and Lilly outside the submitted work.
Publisher Copyright:
© 2019
PY - 2019/8
Y1 - 2019/8
N2 - The optimal management of localized soft tissue sarcomas of the extremities and retroperitoneum involves a high volume multidisciplinary team with expertise in sarcoma. In this review, we will highlight the importance of the sarcoma pathologist and imaging techniques prior to surgery and radiation. In addition, the data on neoadjuvant and adjuvant chemotherapy will be discussed. Finally, consideration is given to the importance of identifying genetic cancer predispositions, multidisciplinary management, long-term survivorship, and the current clinical trials for patients undergoing curative intent management.
AB - The optimal management of localized soft tissue sarcomas of the extremities and retroperitoneum involves a high volume multidisciplinary team with expertise in sarcoma. In this review, we will highlight the importance of the sarcoma pathologist and imaging techniques prior to surgery and radiation. In addition, the data on neoadjuvant and adjuvant chemotherapy will be discussed. Finally, consideration is given to the importance of identifying genetic cancer predispositions, multidisciplinary management, long-term survivorship, and the current clinical trials for patients undergoing curative intent management.
KW - Extremity
KW - Radiation
KW - Retroperitoneum
KW - Soft tissue sarcoma
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=85067236107&partnerID=8YFLogxK
U2 - 10.1016/j.currproblcancer.2019.06.002
DO - 10.1016/j.currproblcancer.2019.06.002
M3 - Review article
C2 - 31221500
AN - SCOPUS:85067236107
VL - 43
SP - 273
EP - 282
JO - Current Problems in Cancer
JF - Current Problems in Cancer
SN - 0147-0272
IS - 4
ER -