Management of dysfunction in the transplanted lung: Experience with 7 clinical cases

David A. Haydock, Elbert P. Trulock, Larry R. Kaiser, Simon R. Knight, Michael K. Pasque, Joel D. Cooper

Research output: Contribution to journalArticlepeer-review

70 Scopus citations


In a series of 34 lung transplant patients, donor lung dysfunction occurred on 7 occasions. One patient underwent retransplantation and the remaining 6 were treated conservatively. Survival was 100% in the donor lung dysfunction group. Percent predicted forced expiratory volume in 1 second, carbon monoxide diffusion, room air oxygen tension, and distance walked in 6 minutes were all lower (p < 0.05) at 1 month after transplantation in those patients with donor lung dysfunction as compared with those without. These differences were not significant at 3 months after transplantation. We conclude that donor lung dysfunction can usually be managed conservatively with satisfactory results. Longer follow-up of this group of patients will be necessary to determine the long-term consequences of early graft injury.

Original languageEnglish
Pages (from-to)635-641
Number of pages7
JournalThe Annals of thoracic surgery
Issue number4
StatePublished - Apr 1992


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