Mammaglobin-A is a target for breast cancer vaccination

Samuel W. Kim; Peter Goedegebuure; William E. Gillanders

doi:10.1080/2162402X.2015.1069940

Mammaglobin-A is a target for breast cancer vaccination

Samuel W. Kim, Peter Goedegebuure, William E. Gillanders

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19 Scopus citations

Abstract

We recently completed a phase 1 clinical trial demonstrating the safety of a mammaglobin-A DNA vaccine in patients with metastatic breast cancer. We are currently enrolling patients with early stage breast cancer in a phase 1b clinical trial. The mammaglobin-A DNA vaccine will be administered concurrently with neoadjuvant endocrine therapy, providing a unique opportunity to examine the impact of vaccination in the tumor microenvironment.

Original language	English
Journal	OncoImmunology
Volume	5
Issue number	2
DOIs	https://doi.org/10.1080/2162402X.2015.1069940
State	Published - Feb 1 2016

Keywords

Cancer vaccine
DNA vaccine
T cells
breast cancer
immunotherapy
mammaglobin-A

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10.1080/2162402X.2015.1069940

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abstract = "We recently completed a phase 1 clinical trial demonstrating the safety of a mammaglobin-A DNA vaccine in patients with metastatic breast cancer. We are currently enrolling patients with early stage breast cancer in a phase 1b clinical trial. The mammaglobin-A DNA vaccine will be administered concurrently with neoadjuvant endocrine therapy, providing a unique opportunity to examine the impact of vaccination in the tumor microenvironment.",

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Mammaglobin-A is a target for breast cancer vaccination

Abstract

Keywords

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