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Malignant renal tumors

  • Bahig M. Shehata
  • , Mina M. Naguib
  • , Jenny Lin
  • , Geetika Khanna

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

The majority of pediatric renal tumors are Wilms’tumors. Of particular concern are those renal neoplasms carrying malignant potential. These entities are given particular attention in this chapter. Universally, partial and radical nephrectomies are used to treat both benign and malignant neoplasms. Chemotherapies have improved the prognosis of many malignant renal tumors, such as Wilms, but others, especially those carrying INI-1 mutations, remain difficult to treat and have high mortality rates. More molecular and genetic research is needed to fully understand and successfully treat this subset of childhood tumor.

Original languageEnglish
Title of host publicationPediatric Malignancies
Subtitle of host publicationPathology and Imaging
PublisherSpringer New York
Pages271-295
Number of pages25
ISBN (Electronic)9781493917297
ISBN (Print)9781493917280
DOIs
StatePublished - Jan 1 2015

Keywords

  • Clear cell sarcoma of the kidney
  • Congenital mesoblastic nephroma
  • Cystic nephroma
  • Kidney
  • Neoplasms
  • Nephroblastomatosis
  • Nephrogenic rests
  • Pediatric
  • Renal
  • Renal cell carcinomas
  • Renal medullary carcinoma
  • Rhabdoid tumor
  • Wilms-tumor

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