Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma

Medicine and Dentistry

• Neoplasm 100%
• Squamous Cell Carcinoma 100%
• Oral Cavity 100%
• Tumor Infiltrating Lymphocyte 100%
• Lymphocytic Infiltration 100%
• RNA Sequence 71%
• Tumor Progression 71%
• Primary Tumor 42%
• T Cell 42%
• Metastatic Carcinoma 28%
• The Cancer Genome Atlas 28%
• C57BL/6 14%
• Gene Expression Profiling 14%
• Short Hairpin RNA 14%
• Growth Inhibition 14%
• Tumor Cell 14%
• Lymph Node 14%
• Flow Cytometry 14%
• Lymph Node Metastasis 14%
• Quantitative Reverse Transcription Polymerase Chain Reaction 14%
• Squamous Cell Carcinoma Cell Line 14%
• Immune Cell Infiltration 14%
• CD3 Antigen 14%
• RNA Knockdown 14%
• Fibroblast 14%

Keyphrases

• Malignant Cells 100%
• Oral Tongue Squamous Cell Carcinoma (OTSCC) 100%
• Tumor-infiltrating Lymphocytes 100%
• CXCL14 100%
• Primary Tumor 16%
• Single-cell RNA Sequencing Data 16%
• MOC2 16%
• Tumor 11%
• Overexpression 11%
• Tumor Growth 11%
• Metastasis 11%
• Cell Tumor 11%
• Tumor Inhibition 11%
• Single-cell RNA Sequencing (scRNA-seq) 11%
• T Cell Depletion 11%
• MOC1 11%
• SiRNA Knockdown 5%
• C57BL 5%
• Immune Response 5%
• Knockdown 5%
• Short Hairpin RNA (shRNA) 5%
• Downregulated Genes 5%
• Tumor Cells 5%
• Quantitative PCR 5%
• Oral Cavity 5%
• Fibroblasts 5%
• Lymph Node 5%
• Flow Cytometry 5%
• Lymph Node Metastasis 5%
• Lymphocyte Infiltration 5%
• Tumor Volume 5%
• Human Tumors 5%
• Immunodeficient Mice 5%
• Expression Change 5%
• Gene Signature 5%
• Non-malignant Cells 5%
• Carcinoma Cell Lines 5%
• Squamous Carcinoma Cells 5%
• Immune Infiltration 5%
• Tumor Growth in Vivo 5%
• CD45+ 5%
• CD3+ T Cells 5%
• Context Effects 5%
• Critical Context 5%

Immunology and Microbiology

• Squamous Cell 100%
• CXCL14 100%
• Lymphocyte 100%
• Tumor-Associated Macrophage 38%
• RNA Sequence 27%
• Tumor Cell 11%
• Lymph Node 11%
• T Cell Depletion 11%
• T Cell 5%
• C57BL 6 Mouse 5%
• Quantitative Reverse Transcription Polymerase Chain Reaction 5%
• Growth Inhibition 5%
• Tumor Volume 5%
• RNA Knockdown 5%
• Squamous Cell Carcinoma Cell Line 5%
• Immune Cell Infiltration 5%
• Fibroblast 5%
• Gene Expression Assay 5%
• CD3 Antigen 5%