MALDI-TOF mass spectrometry misidentification of Cutibacterium namnetense and Cutibacterium modestum: Implications for multiplex PCR phylotyping of Cutibacterium acnes

Joseph McLaughlin; Carey Ann D. Burnham; Andrew McDowell

doi:10.1016/j.anaerobe.2024.102874

MALDI-TOF mass spectrometry misidentification of Cutibacterium namnetense and Cutibacterium modestum: Implications for multiplex PCR phylotyping of Cutibacterium acnes

Joseph McLaughlin
, Carey Ann D. Burnham
, Andrew McDowell

Research output: Contribution to journal › Article › peer-review

Abstract

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) can misidentify Cutibacterium namnetense and Cutibacterium modestum as Cutibacterium acnes. We now describe how such MALDI-TOF MS misidentification explains previous reports of C. acnes isolates that could not be characterised using a multiplex PCR phylotyping assay.

Original language	English
Article number	102874
Journal	Anaerobe
Volume	88
DOIs	https://doi.org/10.1016/j.anaerobe.2024.102874
State	Published - Aug 2024

Keywords

Cutibacterium
MALDI-TOF MS
Misidentification
Multiplex PCR phylotyping

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10.1016/j.anaerobe.2024.102874

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title = "MALDI-TOF mass spectrometry misidentification of Cutibacterium namnetense and Cutibacterium modestum: Implications for multiplex PCR phylotyping of Cutibacterium acnes",

abstract = "Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) can misidentify Cutibacterium namnetense and Cutibacterium modestum as Cutibacterium acnes. We now describe how such MALDI-TOF MS misidentification explains previous reports of C. acnes isolates that could not be characterised using a multiplex PCR phylotyping assay.",

keywords = "Cutibacterium, MALDI-TOF MS, Misidentification, Multiplex PCR phylotyping",

author = "Joseph McLaughlin and Burnham, \{Carey Ann D.\} and Andrew McDowell",

note = "Publisher Copyright: {\textcopyright} 2024 The Author(s)",

year = "2024",

month = aug,

doi = "10.1016/j.anaerobe.2024.102874",

language = "English",

volume = "88",

journal = "Anaerobe",

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T1 - MALDI-TOF mass spectrometry misidentification of Cutibacterium namnetense and Cutibacterium modestum

T2 - Implications for multiplex PCR phylotyping of Cutibacterium acnes

AU - McLaughlin, Joseph

AU - Burnham, Carey Ann D.

AU - McDowell, Andrew

PY - 2024/8

Y1 - 2024/8

N2 - Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) can misidentify Cutibacterium namnetense and Cutibacterium modestum as Cutibacterium acnes. We now describe how such MALDI-TOF MS misidentification explains previous reports of C. acnes isolates that could not be characterised using a multiplex PCR phylotyping assay.

AB - Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) can misidentify Cutibacterium namnetense and Cutibacterium modestum as Cutibacterium acnes. We now describe how such MALDI-TOF MS misidentification explains previous reports of C. acnes isolates that could not be characterised using a multiplex PCR phylotyping assay.

KW - Cutibacterium

KW - MALDI-TOF MS

KW - Misidentification

KW - Multiplex PCR phylotyping

UR - https://www.scopus.com/pages/publications/85195635650

U2 - 10.1016/j.anaerobe.2024.102874

DO - 10.1016/j.anaerobe.2024.102874

M3 - Article

C2 - 38848934

AN - SCOPUS:85195635650

SN - 1075-9964

VL - 88

JO - Anaerobe

JF - Anaerobe

M1 - 102874

ER -

MALDI-TOF mass spectrometry misidentification of Cutibacterium namnetense and Cutibacterium modestum: Implications for multiplex PCR phylotyping of Cutibacterium acnes

Abstract

Keywords

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