Malakoplakia mimicking carcinoma metastatic to lung

E. Crouch, J. Wright, V. White, A. Churg

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21 Scopus citations


Malakoplakia is a rare inflammatory disorder which infrequently involves sites outside of the lower genitourinary or gastrointestinal tract. We report a case of malakoplakia in which the patient presented with a left renal mass and bilateral pulmonary nodules suggestive of metastatic renal carcinoma. Postmortem cultures of the lesions grew E. coli; macrophages at both sides contained gram-negative bacilli and numerous Michaelis-Gutmann bodies. X-ray spectroscopic analysis of the bodies showed wide variation in calcium, phosphorus, and iron content, suggesting that Michaelis-Gutmann bodies were formed in part by the deposition of amorphous salts.

Original languageEnglish
Pages (from-to)151-156
Number of pages6
JournalAmerican Journal of Surgical Pathology
Issue number2
StatePublished - 1984


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