Magnetic resonance brain imaging lacks sensitivity for AIDS associated cytomegalovirus encephalitis

David B. Clifford, José R. Arribas, Gregory A. Storch, Warren Tourtellote, Franz J. Wippold

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

Six patients are presented who died with active cytomegalovirus (CMV) encephalitis in whom brain MR scans within 25 days of death failed to reveal distinctive findings suggesting the diagnosis of CMV encephalitis. While MR scanning is crucial to evulation of AIDS patients developing neurologic complications, it is not sensitive to the presence of CMV encephalitis even when it is quite severe. The diagnosis of CMV encephalitis during life rests on characteristic clinical findings supported by typical laboratory measures including the presence of CMV DNA in cerebrospinal fluid as detected by polymerase chain reaction.

Original languageEnglish
Pages (from-to)397-403
Number of pages7
JournalJournal of NeuroVirology
Volume2
Issue number6
DOIs
StatePublished - Dec 1996

Keywords

  • Cytomegalovirus
  • Encephalitis diagnosis
  • Magnetic resonance imaging
  • Viral encephalitis

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