TY - JOUR
T1 - Lysine derived cross-links are present in a non-elastin, proline-rich protein fraction of Iguana iguana eggshell
AU - Cox, David L.
AU - Mecham, Robert P.
AU - Sexton, Owen J.
N1 - Funding Information:
Supported by USPHS Grants PO1-HL16118 and IT32 HL07317.
PY - 1982
Y1 - 1982
N2 - 1. 1. Eggshell of Iguana iguana contains a variety of lysine-derived cross-linking amino acids apparently identical with some that occur in elastin. 2. 2. Quantification of desmosine by amino acid analysis and radioimmunoassay gave estimates of 217 ng per mg and 109 ng per mg (dry weights), respectively. 3. 3. [3H]NaBH4 reduction of eggshell protein established presence of lysine-derived aldehydes, allysine and allysine-aldol. 4. 4. Enzymatic and chemical treatments indicate these cross-links occur in a non-elastin eggshell protein. 5. 5. Iguana eggshell protein is unusually proline-rich, containing almost 440 proline residues per thousand.
AB - 1. 1. Eggshell of Iguana iguana contains a variety of lysine-derived cross-linking amino acids apparently identical with some that occur in elastin. 2. 2. Quantification of desmosine by amino acid analysis and radioimmunoassay gave estimates of 217 ng per mg and 109 ng per mg (dry weights), respectively. 3. 3. [3H]NaBH4 reduction of eggshell protein established presence of lysine-derived aldehydes, allysine and allysine-aldol. 4. 4. Enzymatic and chemical treatments indicate these cross-links occur in a non-elastin eggshell protein. 5. 5. Iguana eggshell protein is unusually proline-rich, containing almost 440 proline residues per thousand.
UR - http://www.scopus.com/inward/record.url?scp=0020014681&partnerID=8YFLogxK
U2 - 10.1016/0305-0491(82)90515-6
DO - 10.1016/0305-0491(82)90515-6
M3 - Article
C2 - 6181935
AN - SCOPUS:0020014681
VL - 72
SP - 619
EP - 623
JO - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
JF - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
SN - 0305-0491
IS - 4
ER -