Lung volume reduction surgery for emphysema

Matthew Brenner, Roger Yusen, Robert McKenna, Frank Sciurba, Arthur F. Gelb, Richard Fischel, Julie Swain, John C. Chen, Fernando Kafie, Stephen S. Lefrak

Research output: Contribution to journalReview articlepeer-review

96 Scopus citations


There has been dramatic resurgence of interest in surgical treatment of emphysema, particularly 'lung volume reduction' procedures. Recent studies have demonstrated improvements in pulmonary function, lung mechanics, exercise tolerance, and quality of life in selected patients following volume reduction procedures. However, considerable uncertainty remains regarding overall benefit, optimal patient selection, operative techniques, and duration of response. This review summarizes current approaches to lung volume reduction surgery, available clinical outcome information, selection criteria, and physiologic mechanisms of response, and discuSSes the potential role for surgical volume reduction in treatment of emphysema. Recent data appear to support the efficacy of bilateral staple lung volume reduction surgery in patients with severe symptomatic heterogeneously distributed emphysema. Further studies will be needed to determine relative value of different operative techniques and benefit in patients with other clinical presentations.

Original languageEnglish
Pages (from-to)205-218
Number of pages14
Issue number1
StatePublished - 1996


  • emphysema
  • laser
  • lung
  • reduction
  • staple
  • surgery
  • volume


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