Lung transplantation at Barnes-Jewish Hospital and Washington University in St. Louis.

Ramsey R. Hachem, G. Alexander Patterson, Elbert P. Trulock

Research output: Contribution to journalArticlepeer-review


The lung transplant program at Washington University and Barnes-Jewish Hospital has performed more than 1,000 lung transplants since 1988. The most common operation during this time period has been bilateral-lung transplantation. The LAS has changed lung recipients' diagnoses nationally and at our center. IPF accounts for approximately 25% of recipients at our program and 33% of recipients nationally. Although more severely and acutely ill patients are now coming to transplantation, the long-term outcomes after transplantation have not changed substantially. The incidence of all forms of rejection is high after lung transplantation despite modern immunosuppressive regimens and surveillance techniques. Long-term survival after lung transplantation remains disappointing. In the most recent cohort, the 5-year survival is 64%, but this is significantly worse than survival after kidney, liver, and heart transplantation.

Original languageEnglish
Pages (from-to)227-234
Number of pages8
JournalClinical transplants
StatePublished - 2010


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