Low-cost compact multispectral spatial frequency domain imaging prototype for tissue characterization

  • Mohsen Erfanzadeh
  • , Sreyankar Nandy
  • , Patrick D. Kumavor
  • , Quing Zhu

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

We present a low-cost, compact, and multispectral spatial frequency domain imaging prototype. Illumination components, including 9 LEDs (660 nm – 950 nm) placed on a custom-designed printed circuit board, linear and rotational motors, a printed sinusoidal pattern, and collimation and projection optics as well as the detection components are incorporated in a compact custom-designed 3D-printed probe. Reconstruction of absorption and reduced scattering coefficients is evaluated via imaging tissue mimicking phantoms and potentials of the probe for biological tissue imaging are evaluated via imaging human ovarian tissue ex vivo.

Original languageEnglish
Article number#335885
Pages (from-to)5503-5510
Number of pages8
JournalBiomedical Optics Express
Volume9
Issue number11
DOIs
StatePublished - Nov 1 2018

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