Longitudinal Trends in Glycemic Outcomes and Technology Use for Over 48,000 People with Type 1 Diabetes (2016–2022) from the T1D Exchange Quality Improvement Collaborative

  • on behalf of the T1DX-QI Collaborative
  • , Osagie Ebekozien
  • , Ann Mungmode
  • , Janine Sanchez
  • , Saketh Rompicherla
  • , Carla Demeterco-Berggren
  • , Ruth S. Weinstock
  • , Laura M. Jacobsen
  • , Georgia Davis
  • , Alexis McKee
  • , Halis K. Akturk
  • , David M. Maahs
  • , Manmohan K. Kamboj

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Previous studies revealed that hemoglobin A1c (HbA1c) increased overall in the United States in the past decade. In addition, health inequities in type 1 diabetes (T1D) outcomes by race/ethnicity and insurance type persist. This study examines the trends in HbA1c from 2016 to 2022 stratified by race/ethnicity and insurance in a large multicenter national database. Research Design and Methods: We analyzed glycemic outcomes and diabetes device use trends for >48,000 people living with type 1 diabetes (PwT1D) from 3 adult and 12 pediatric centers in the T1D Exchange Quality Improvement Collaborative (T1DX-QI), comparing data from 2016 to 2017 with data from 2021 to 2022. Results: The mean HbA1c in 2021–2022 was lower at 8.4% compared with the mean HbA1c in 2016–2017 of 8.7% (0.3% improvement; P < 0.01). Over the same period, the percentage of PwT1D using a continuous glucose monitor (CGM), insulin pump, or hybrid closed-loop system increased (45%, 12%, and 33%, respectively). However, these improvements were not equitably demonstrated across racial/ethnic groups or insurance types. Racial/ethnic and insurance-based inequities persisted over all 7 years across all outcomes; comparing non-Hispanic White and non-Hispanic Black PwT1D, disparate gaps in HbA1c (1.2%–1.6%), CGM (30%), pump (25%–35%), and hybrid-closed loop system (up to 20%) are illuminated. Conclusion: Population-level data on outcomes, including HbA1c, can provide trends and insights into strategies to improve health for PwT1D. The T1DX-QI cohort showed a significant improvement in HbA1c from 2016 to 2022. Improvements in diabetes device use are also demonstrated. However, these increases were inconsistent across all racial/ethnic groups or insurance types, an important focus for future T1D population health improvement work.

Original languageEnglish
Pages (from-to)765-773
Number of pages9
JournalDiabetes Technology and Therapeutics
Volume25
Issue number11
DOIs
StatePublished - Nov 1 2023

Keywords

  • HbA1c
  • Health equity
  • Learning health system
  • Quality improvement
  • Real-world data
  • Type 1 diabetes

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