TY - JOUR
T1 - Long-term follow-up of couples after hamster egg penetration testing
AU - O'Shea, D. L.
AU - Odem, R. R.
AU - Cholewa, C.
AU - Gast, M. J.
PY - 1993
Y1 - 1993
N2 - Objective: To determine the clinical usefulness of the zona-free hamster egg penetration test as a long-term prognostic indicator for future pregnancy. Setting: Division of Reproductive Endocrinology and Infertility at the Washington University Medical Center. Participants: All couples (n = 148) who had a hamster egg penetration assay performed between March 1, 1985 and December 31, 1986 were identified and followed with direct or telephone contact up to 68 months after the initial assay. Main Outcome Measure: The monthly fecundity rates using life table analysis and the 5-year incidence of pregnancy were categorized by the percentage of hamster eggs penetrated and by history of previous urologic surgery. Results: There were no significant differences in the rate nor incidence of pregnancy in couples with hamster egg penetration scores of 0%, >0% and ≤10%, >10%, and ≤20%, or >20%. Although men with previous urologic surgery tended to have lower scores, there was no significant difference in the 5-year incidence of pregnancy. Conclusion: The hamster egg penetration score is not predictive of incidence of pregnancy nor time to conception.
AB - Objective: To determine the clinical usefulness of the zona-free hamster egg penetration test as a long-term prognostic indicator for future pregnancy. Setting: Division of Reproductive Endocrinology and Infertility at the Washington University Medical Center. Participants: All couples (n = 148) who had a hamster egg penetration assay performed between March 1, 1985 and December 31, 1986 were identified and followed with direct or telephone contact up to 68 months after the initial assay. Main Outcome Measure: The monthly fecundity rates using life table analysis and the 5-year incidence of pregnancy were categorized by the percentage of hamster eggs penetrated and by history of previous urologic surgery. Results: There were no significant differences in the rate nor incidence of pregnancy in couples with hamster egg penetration scores of 0%, >0% and ≤10%, >10%, and ≤20%, or >20%. Although men with previous urologic surgery tended to have lower scores, there was no significant difference in the 5-year incidence of pregnancy. Conclusion: The hamster egg penetration score is not predictive of incidence of pregnancy nor time to conception.
KW - Hamster egg penetration test
KW - fecundity
KW - sperm penetration assay
KW - spermatozoa
UR - http://www.scopus.com/inward/record.url?scp=0027485263&partnerID=8YFLogxK
U2 - 10.1016/S0015-0282(16)56407-3
DO - 10.1016/S0015-0282(16)56407-3
M3 - Article
C2 - 8243683
AN - SCOPUS:0027485263
VL - 60
SP - 1040
EP - 1045
JO - Fertility and Sterility
JF - Fertility and Sterility
SN - 0015-0282
IS - 6
ER -