Long non-coding RNA SNHG8 drives stress granule formation in tauopathies

Keyphrases

• Non-coding RNA (ncRNA) 100%
• Tauopathy 100%
• Stress Granule Formation 100%
• SNHG8 100%
• TIA1 50%
• RNA-binding Protein 33%
• Differentially Expressed 33%
• MAPT mutation 33%
• Mouse Model 16%
• Overexpression 16%
• Dysregulation 16%
• Neurodegenerative Diseases 16%
• Alzheimer's Disease Brain 16%
• Induced Stress 16%
• Rare mutation 16%
• Causal Factors 16%
• Tau Protein 16%
• Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) 16%
• Transcriptomic Changes 16%
• MAPT Gene 16%
• Progressive Supranuclear Palsy 16%
• Mutant Alleles 16%
• Stress Granules 16%
• Heterogenous Groups 16%
• Tau Aggregation 16%
• Coding Potential 16%
• Stem Cell-derived Neurons 16%
• Isogenic Controls 16%
• Immortalized Cell 16%
• Reduced Stress 16%
• Driving Stress 16%
• P301L 16%
• FTLD-tau 16%

Biochemistry, Genetics and Molecular Biology

• Long Non-Coding RNA 100%
• Stress Granule 100%
• Tau 66%
• TIA1 50%
• RNA-binding Protein 33%
• Stem Cell 16%
• Mouse Model 16%
• Allele 16%
• Transcription 16%
• Non-Coding RNA 16%
• Transcriptomics 16%
• CRISPR 16%
• Tau Protein 16%

Neuroscience

• Long Non-Coding RNA 100%
• Tauopathy 100%
• RNA-binding Protein 33%
• Alzheimer's Disease 16%
• In Vitro 16%
• Frontotemporal Dementia 16%
• Neurodegenerative Disorder 16%
• Stem Cell 16%
• Transcriptomics 16%
• Tau Protein 16%
• Non-Coding RNA 16%
• Progressive Supranuclear Palsy 16%
• CRISPR 16%
• Nucleolysin TIA 1 Isoform P40 16%