Location, Location, Location: FoxM1 Mediates β-Catenin Nuclear Translocation and Promotes Glioma Tumorigenesis

Angela Bowman, Roel Nusse

Research output: Contribution to journalShort surveypeer-review

35 Scopus citations

Abstract

Genetic alterations in the Wnt/β-catenin/TCF-signaling pathway are commonly found in human tumors, but not in glioblastomas. In this issue of Cancer Cell, Zhang et al. report that FoxM1 mediates β-catenin nuclear translocation in glioblastoma, suggesting a novel mechanism for glioblastoma progression in the absence of conventional Wnt/β-catenin pathway activation.

Original languageEnglish
Pages (from-to)415-416
Number of pages2
JournalCancer Cell
Volume20
Issue number4
DOIs
StatePublished - Oct 18 2011

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