Location, Location, Location: FoxM1 Mediates β-Catenin Nuclear Translocation and Promotes Glioma Tumorigenesis

Angela Bowman; Roel Nusse

doi:10.1016/j.ccr.2011.10.003

Location, Location, Location: FoxM1 Mediates β-Catenin Nuclear Translocation and Promotes Glioma Tumorigenesis

Angela Bowman, Roel Nusse

Research output: Contribution to journal › Short survey › peer-review

39 Scopus citations

Abstract

Genetic alterations in the Wnt/β-catenin/TCF-signaling pathway are commonly found in human tumors, but not in glioblastomas. In this issue of Cancer Cell, Zhang et al. report that FoxM1 mediates β-catenin nuclear translocation in glioblastoma, suggesting a novel mechanism for glioblastoma progression in the absence of conventional Wnt/β-catenin pathway activation.

Original language	English
Pages (from-to)	415-416
Number of pages	2
Journal	Cancer Cell
Volume	20
Issue number	4
DOIs	https://doi.org/10.1016/j.ccr.2011.10.003
State	Published - Oct 18 2011

Access to Document

10.1016/j.ccr.2011.10.003

Cite this

@article{ba837a7886164a39b85a5e809c796e15,

title = "Location, Location, Location: FoxM1 Mediates β-Catenin Nuclear Translocation and Promotes Glioma Tumorigenesis",

abstract = "Genetic alterations in the Wnt/β-catenin/TCF-signaling pathway are commonly found in human tumors, but not in glioblastomas. In this issue of Cancer Cell, Zhang et al. report that FoxM1 mediates β-catenin nuclear translocation in glioblastoma, suggesting a novel mechanism for glioblastoma progression in the absence of conventional Wnt/β-catenin pathway activation.",

author = "Angela Bowman and Roel Nusse",

year = "2011",

month = oct,

day = "18",

doi = "10.1016/j.ccr.2011.10.003",

language = "English",

volume = "20",

pages = "415--416",

journal = "Cancer Cell",

issn = "1535-6108",

number = "4",

}

TY - JOUR

T1 - Location, Location, Location

T2 - FoxM1 Mediates β-Catenin Nuclear Translocation and Promotes Glioma Tumorigenesis

AU - Bowman, Angela

AU - Nusse, Roel

PY - 2011/10/18

Y1 - 2011/10/18

N2 - Genetic alterations in the Wnt/β-catenin/TCF-signaling pathway are commonly found in human tumors, but not in glioblastomas. In this issue of Cancer Cell, Zhang et al. report that FoxM1 mediates β-catenin nuclear translocation in glioblastoma, suggesting a novel mechanism for glioblastoma progression in the absence of conventional Wnt/β-catenin pathway activation.

AB - Genetic alterations in the Wnt/β-catenin/TCF-signaling pathway are commonly found in human tumors, but not in glioblastomas. In this issue of Cancer Cell, Zhang et al. report that FoxM1 mediates β-catenin nuclear translocation in glioblastoma, suggesting a novel mechanism for glioblastoma progression in the absence of conventional Wnt/β-catenin pathway activation.

UR - http://www.scopus.com/inward/record.url?scp=80054738983&partnerID=8YFLogxK

U2 - 10.1016/j.ccr.2011.10.003

DO - 10.1016/j.ccr.2011.10.003

M3 - Short survey

C2 - 22014565

AN - SCOPUS:80054738983

SN - 1535-6108

VL - 20

SP - 415

EP - 416

JO - Cancer Cell

JF - Cancer Cell

IS - 4

ER -

Location, Location, Location: FoxM1 Mediates β-Catenin Nuclear Translocation and Promotes Glioma Tumorigenesis

Abstract

Access to Document

Other files and links

Fingerprint

Cite this