Liver transplantation in acute liver failure

Acute liver failure (ALF) is a Gl emergency that continues to be a therapeutic challenge. Aggressive supportive care in an experienced intensive care facility has improved survival rates of patients with ALF. Liver transplantation is considered an important therapeutic option for ALF patients who have poor prognosis. Prognosticating the outcome in ALF is difficult and the decision to transplant needs frequent monitoring and a multidisciplinary approach from an experienced team. For these reasons, patients with ALF are best cared for in an inpatient ICU setting. Early referrals to such tertiary-care centers with the necessary experience and expertise provide the best outcomes for patients presenting with ALF.