Abstract
We report the findings from liver biopsies of three patients with polyglandular autoimmune disease type 1. The livers in two patients had histologic features of chronic hepatitis that eventuated in bridging fibrosis and cirrhosis over a period of several years. Nonspecific lobular and portal tract inflammation was present in the liver biopsy of the third patient. Although these patients did not have liver-specific autoantibodies, the liver disease in polyglandular autoimmune disease type 1 possibly represents an expression of autoimmune hepatitis.
Original language | English |
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Pages (from-to) | 625-636 |
Number of pages | 12 |
Journal | Pediatric Pathology and Laboratory Medicine |
Volume | 16 |
Issue number | 4 |
DOIs | |
State | Published - 1996 |
Keywords
- autoimmune
- hepatitis
- liver
- polyglandular autoimmune disease