Lipophosphoglycan (LPG) and the identification of virulence genes in the protozoan parasite Leishmania

Stephen M. Beverley, Salvatore J. Turco

Research output: Contribution to journalReview article

138 Scopus citations

Abstract

Leishmania exploits several strategies to survive within the phagolysosome of vertebrate macrophages and be transmitted by sand fly vectors. Recent advances in functional genetic analysis provide a new avenue for identifying genes implicated in the infectious cycle of the parasite, such as those necessary for the synthesis and expression of the key surface glycoconjugate, lipophosphoglycan (LPG).

Original languageEnglish
Pages (from-to)35-40
Number of pages6
JournalTrends in Microbiology
Volume6
Issue number1
DOIs
StatePublished - Jan 1 1998

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