Lipase Elevation in Patients With COVID-19

Julia McNabb-Baltar, David X. Jin, Amit S. Grover, Walker D. Redd, Joyce C. Zhou, Kelly E. Hathorn, Thomas R. McCarty, Ahmad N. Bazarbashi, Lin Shen, Walter W. Chan

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

INTRODUCTION: Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19. METHODS: A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19. RESULTS: Of 71 patients, 9 (12.1%) developed hyperlipasemia, with 2 (2.8%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms. DISCUSSION: Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.

Original languageEnglish
Pages (from-to)1286-1288
Number of pages3
JournalThe American journal of gastroenterology
Volume115
Issue number8
DOIs
StatePublished - Aug 1 2020

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