Linking osteopetrosis and pycnodysostosis: Regulation of cathepsin K expression by the microphthalmia transcription factor family

Keyphrases

• Osteopetrosis 100%
• Transcription Factor Family 100%
• Cathepsin K 100%
• Microphthalmia-associated Transcription Factor 100%
• Pycnodysostosis 100%
• Mitf 75%
• Osteoclast 25%
• Transcription Factor E3 (TFE3) 25%
• Dominant Negative 16%
• K Promoter 16%
• Transcription Factor 8%
• Overexpression 8%
• Protein Degradation 8%
• Family Members 8%
• Autosomal Recessive 8%
• Rodents 8%
• Gene-deficient Mice 8%
• Helix 8%
• Tumor Invasiveness 8%
• Protein Components 8%
• Dimerization 8%
• Age-related Changes 8%
• Transcriptional Targets 8%
• Human Breast Cancer 8%
• Osteoclast Function 8%
• Genetic Matching 8%
• Bone Matrix 8%
• Human Malignancies 8%
• Promoter Activity 8%
• Genetic Condition 8%
• Human Osteoblasts 8%
• Osteosclerosis 8%
• Cysteine Protease 8%
• Recessive mutation 8%
• Functional Requirements 8%
• Bone Homeostasis 8%
• Up-regulated Expression 8%
• Family Assistance 8%

Biochemistry, Genetics and Molecular Biology

• Cathepsin K 100%
• Microphthalmia-Associated Transcription Factor 100%
• Osteoclast 41%
• TFE3 25%
• Promoter Region 16%
• Wild Type 8%
• Genetics 8%
• Allele 8%
• Homeostasis 8%
• Transcription Factors 8%
• Dimerization 8%
• Autosomal Recessive Inheritance 8%
• Cysteine Protease 8%
• TFEB 8%
• Messenger RNA 8%