Ligand trap for the activin type IIA receptor protects against vascular disease and renal fibrosis in mice with chronic kidney disease

Keyphrases

• Chronic Kidney Disease 100%
• Vascular Disease 100%
• Activin 100%
• Ligand Trap 100%
• Renal Fibrosis 100%
• Receptor Subtypes 87%
• Activin Receptor 87%
• Dickkopf-1 (DKK1) 25%
• Mouse Model 12%
• Kidney 12%
• Extracellular Domain 12%
• Proteinuria 12%
• Vascular Smooth muscle Cells 12%
• Cardiovascular Mortality 12%
• Klotho 12%
• Renal Repair 12%
• Atherosclerotic Calcification 12%
• Osteogenic Transition 12%
• Neointimal 12%
• Pathogenic Factors 12%
• Putative Drug Targets 12%
• Smooth muscle 12%
• Bone Disorders 12%
• Dedifferentiation 12%
• Smad3 Phosphorylation 12%
• Plaque Calcification 12%
• Early Chronic Kidney Disease 12%
• Portmanteau 12%
• IgG Fc Fragments 12%

Medicine and Dentistry

• Receptor 100%
• Vascular Disease 100%
• Chronic Kidney Disease 100%
• Kidney Fibrosis 100%
• Activin 100%
• Activin Receptor 77%
• Proteinuria 11%
• Vascular Smooth Muscle 11%
• Cardiovascular Mortality 11%
• Cell Dedifferentiation 11%
• Smooth Muscle 11%
• Immunoglobulin Fc Fragment 11%
• Bone Disease 11%

Biochemistry, Genetics and Molecular Biology

• Activin 100%
• Activin Receptor 100%
• Mouse Model 14%
• Cardiovascular Mortality 14%
• Cell Dedifferentiation 14%