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Ligand effects on phase separation of multivalent macromolecules
Kiersten M. Ruff
, Furqan Dar
,
Rohit V. Pappu
Department of Biomedical Engineering
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
DBBS - Plant and Microbial Biosciences
DBBS - Computational and Systems Biology
Center of Regenerative Medicine
Institute of Clinical and Translational Sciences (ICTS)
Hope Center for Neurological Disorders
DBBS - Biochemistry, Biophysics, and Structural Biology
Research output
:
Contribution to journal
›
Article
›
peer-review
96
Scopus citations
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Keyphrases
Macromolecules
100%
Ligand Effects
100%
Sticker
100%
Phase Separation
100%
Multivalent
100%
Phase Transition
60%
Phase Behavior
40%
Spatial Control
20%
Temporal Control
20%
Cellular Processes
20%
Monovalent Cations
20%
Relative Affinity
20%
Biomolecules
20%
Ligand-mediated
20%
Structural Organization
20%
Valence
20%
Biomolecular Condensates
20%
Ligand Concentration
20%
Modulatory Effects
20%
Covalent Crosslinking
20%
Endogenous Levels
20%
Null Effects
20%
Multivalent Ligands
20%
Dilute Phase
20%
Use Theory
20%
Non-stoichiometric
20%
Reversible Phase Transition
20%
Phase Concentration
20%
Biochemistry, Genetics and Molecular Biology
Macromolecule
100%
Phase Separation
100%
Cross-Link
50%