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Ligand binding results in divalent cation displacement from the α
2
β
1
integrin I domain: Evidence from terbium luminescence spectroscopy
S. Kent Dickeson
, Maitrayee Bhattacharyya-Pakrasi
, Nancy L. Mathis
, Paul H. Schlesinger
, Samuel A. Santoro
Department of Cell Biology & Physiology
Center for the Investigation of Membrane Excitability Diseases
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
DBBS - Molecular Cell Biology
Research output
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Contribution to journal
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Article
›
peer-review
33
Scopus citations
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Dive into the research topics of 'Ligand binding results in divalent cation displacement from the α
2
β
1
integrin I domain: Evidence from terbium luminescence spectroscopy'. Together they form a unique fingerprint.
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Keyphrases
Ligand Binding
100%
Integrin
100%
Photoluminescence Spectroscopy
100%
Divalent Cations
100%
I-domain
100%
Cation Displacement
100%
Terbium Fluorescence
100%
Tb3+
63%
Collagen
45%
Propeptide
27%
Recombinant
18%
Mg2+
18%
Mn2+
18%
Cell Surface
9%
Dissociation
9%
Ligand Complexes
9%
Incubation
9%
Single-molecule Fluorescence Resonance Energy Transfer (smFRET)
9%
Carboxyl
9%
Ligand Effects
9%
Binding Activity
9%
Binding Properties
9%
Metal-free
9%
Cation Binding Site
9%
Metal Ions
9%
Saturable
9%
Laminin Receptor
9%
Trivalent Cations
9%
Terbium Ion
9%
Ion Displacement
9%
Biochemistry, Genetics and Molecular Biology
Ligand Binding
100%
Integrin
100%
Binding Site
20%
C-Terminus
20%
Fluorescence Resonance Energy Transfer
20%
Binding Affinity
20%
Laminin
20%
Ion Displacement
20%