TY - JOUR
T1 - Lensfree on-chip microscopy and tomography for biomedical applications
AU - Isikman, Serhan O.
AU - Bishara, Waheb
AU - Mudanyali, Onur
AU - Sencan, Ikbal
AU - Su, Ting Wei
AU - Tseng, Derek K.
AU - Yaglidere, Oguzhan
AU - Sikora, Uzair
AU - Ozcan, Aydogan
N1 - Funding Information:
Manuscript received May 15, 2011; revised June 29, 2011; accepted June 29, 2011. Date of publication July 12, 2011; date of current version June 1, 2012. This work was supported by the Gates Foundation, Vodafone Americas Foundation, and National Science Foundation (NSF) BISH program under Award # 0754880 and Award 0930501. The work of A. Ozcan was supported by NSF CAREER Award, the ONR Young Investigator Award 2009, and the National Institutes of Health (NIH) Director’s New Innovator Award DP2OD006427 from the Office of The Director, NIH.
PY - 2012
Y1 - 2012
N2 - Lensfree on-chip holographic microscopy is an emerging technique that offers imaging of biological specimens over a large field-of-view without using any lenses or bulky optical components. Lending itself to a compact, cost-effective, and mechanically robust architecture, lensfree on-chip holographic microscopy can offer an alternative toolset addressing some of the emerging needs of microscopic analysis and diagnostics in low-resource settings, especially for telemedicine applications. In this study, we summarize the latest achievements in lensfree optical microscopy based on partially coherent on-chip holography, including portable telemedicine microscopy, cell-phone-based microscopy, and field-portable optical tomographic microscopy. We also discuss some of the future directions for telemedicine microscopy and its prospects to help combat various global health challenges.
AB - Lensfree on-chip holographic microscopy is an emerging technique that offers imaging of biological specimens over a large field-of-view without using any lenses or bulky optical components. Lending itself to a compact, cost-effective, and mechanically robust architecture, lensfree on-chip holographic microscopy can offer an alternative toolset addressing some of the emerging needs of microscopic analysis and diagnostics in low-resource settings, especially for telemedicine applications. In this study, we summarize the latest achievements in lensfree optical microscopy based on partially coherent on-chip holography, including portable telemedicine microscopy, cell-phone-based microscopy, and field-portable optical tomographic microscopy. We also discuss some of the future directions for telemedicine microscopy and its prospects to help combat various global health challenges.
KW - Cell-phone microscopy
KW - global health
KW - holographic pixel uper-resolution
KW - lensfree imaging
KW - lensfree tomography
KW - lensless on-chip imaging
KW - telemedicine microscopy
UR - http://www.scopus.com/inward/record.url?scp=84862297430&partnerID=8YFLogxK
U2 - 10.1109/JSTQE.2011.2161460
DO - 10.1109/JSTQE.2011.2161460
M3 - Article
AN - SCOPUS:84862297430
SN - 1077-260X
VL - 18
SP - 1059
EP - 1072
JO - IEEE Journal on Selected Topics in Quantum Electronics
JF - IEEE Journal on Selected Topics in Quantum Electronics
IS - 3
M1 - 5944945
ER -