TY - JOUR
T1 - Lensfree on-chip imaging using nanostructured surfaces
AU - Khademhosseinieh, Bahar
AU - Sencan, Ikbal
AU - Biener, Gabriel
AU - Su, Ting Wei
AU - Coskun, Ahmet F.
AU - Tseng, Derek
AU - Ozcan, Aydogan
N1 - Funding Information:
The authors acknowledge the support of AFOSR (under Project No. 08NE255), NSF BISH program (under Award No. 0754880), and NIH (under Grant No. 1R21EB009222-01).
PY - 2010/4/26
Y1 - 2010/4/26
N2 - We introduce the use of nanostructured surfaces for lensfree on-chip microscopy. In this incoherent on-chip imaging modality, the object of interest is directly positioned onto a nanostructured thin metallic film, where the emitted light from the object plane, after being modulated by the nanostructures, diffracts over a short distance to be sampled by a detector-array without the use of any lenses. The detected far-field diffraction pattern then permits rapid reconstruction of the object distribution on the chip at the subpixel level using a compressive sampling algorithm. This imaging modality based on nanostructured substrates could especially be useful to create lensfree fluorescent microscopes on a compact chip.
AB - We introduce the use of nanostructured surfaces for lensfree on-chip microscopy. In this incoherent on-chip imaging modality, the object of interest is directly positioned onto a nanostructured thin metallic film, where the emitted light from the object plane, after being modulated by the nanostructures, diffracts over a short distance to be sampled by a detector-array without the use of any lenses. The detected far-field diffraction pattern then permits rapid reconstruction of the object distribution on the chip at the subpixel level using a compressive sampling algorithm. This imaging modality based on nanostructured substrates could especially be useful to create lensfree fluorescent microscopes on a compact chip.
UR - http://www.scopus.com/inward/record.url?scp=77952374186&partnerID=8YFLogxK
U2 - 10.1063/1.3405719
DO - 10.1063/1.3405719
M3 - Article
AN - SCOPUS:77952374186
SN - 0003-6951
VL - 96
JO - Applied Physics Letters
JF - Applied Physics Letters
IS - 17
M1 - 171106
ER -