@article{571c10418ef448b3a926752f262525c4,
title = "Left Atrium Measurements via Computed Tomography Pulmonary Angiogram as a Predictor of Diastolic Dysfunction",
abstract = "Purpose Left atrium (LA) enlargement on echocardiography may be an indicator of diastolic dysfunction (DD). It is not well known if computed tomography pulmonary angiography (CTPA) can detect DD. Methods A total of 127 patients who underwent both CTPA and echo within 48 hours were analyzed retrospectively. Left atrium diameters from CTPA were correlated with echo and evaluated against degrees of DD. Computed tomography pulmonary angiography pulmonary artery (PA)/aorta ratio was analyzed as a tool to detect pulmonary hypertension. Results There were 42% of patients who had DD. There was a strong correlation between LA size on CTPA and echo (r = 0.78). An LA greater than 4.0 cm gave a sensitivity of 68.1% and specificity of 73.9% for DD detection. A PA/aorta cutoff greater than 0.84 yielded a sensitivity of 84% and specificity of 33% for pulmonary hypertension. Conclusions Computed tomography pulmonary angiography measurements of LA and PA/aorta ratio correlate strongly with equivalent findings on echo. We suggest that LA and PA/aorta measurements be included on chest CTPA reports.",
keywords = "computed tomography (CT), diastolic dysfunction, echocardiography, left atrium, pulmonary hypertension",
author = "Lick, {Adam N.} and Raman Danrad and Smith, {David L.} and Lammi, {Matthew R.}",
note = "Funding Information: From the *School of Medicine, †Department of Radiology, and ‡Department of Internal Medicine, Section of Pulmonary/Critical Care & Allergy/Immunology, Louisiana State University Health Sciences Center, New Orleans, LA. Received for publication August 30, 2016; accepted December 14, 2016. Correspondence to: Matthew R. Lammi, MD, MSCR, Section of Pulmonary/Critical Care & Allergy/Immunology, Louisiana State University Health Sciences Center, 1901 Perdido Street, Suite 3205, New Orleans, LA 70112 (e‐mail: mlammi@lsuhsc.edu). Funding: This research was funded by grant #T35HL105350 from the National Heart, Lung and Blood Institute. Supported in part by the National Institute of General Medical Sciences of the National Institutes of Health under award number U54 GM104940 (M.R.L.). Supported in part by National Institute of General Medical Sciences Cardiovascular Centers of Biomedical Research Excellence grant 1P306M206392-01A1 (M.R.L.). Disclosures: The authors declare no conflict of interest. Copyright {\textcopyright} 2017 Wolters Kluwer Health, Inc. All rights reserved. DOI: 10.1097/RCT.0000000000000597 Publisher Copyright: Copyright {\textcopyright} 2017 Wolters Kluwer Health, Inc. All rights reserved.",
year = "2017",
month = sep,
day = "1",
doi = "10.1097/RCT.0000000000000597",
language = "English",
volume = "41",
pages = "792--797",
journal = "Journal of Computer Assisted Tomography",
issn = "0363-8715",
number = "5",
}