TY - JOUR
T1 - Leber hereditary optic neuropathy mimicking neuromyelitis optica
AU - McClelland, Collin M.
AU - Van Stavern, Gregory P.
AU - Tselis, Alex C.
PY - 2011/9/1
Y1 - 2011/9/1
N2 - Leber hereditary optic neuropathy (LHON) is rarely associated with multiple sclerosis-like features. We present a case of a 65-year-old African American woman with LHON masquerading as neuromyelitis optica (NMO). We highlight the features of the clinical examination and MRI that were suggestive of an alternative diagnosis and review the literature regarding LHON and multiple sclerosis. The diagnosis of LHON should be considered in all cases of acute or subacute bilateral optic neuropathy, including presumed seronegative NMO.
AB - Leber hereditary optic neuropathy (LHON) is rarely associated with multiple sclerosis-like features. We present a case of a 65-year-old African American woman with LHON masquerading as neuromyelitis optica (NMO). We highlight the features of the clinical examination and MRI that were suggestive of an alternative diagnosis and review the literature regarding LHON and multiple sclerosis. The diagnosis of LHON should be considered in all cases of acute or subacute bilateral optic neuropathy, including presumed seronegative NMO.
UR - http://www.scopus.com/inward/record.url?scp=80052271802&partnerID=8YFLogxK
U2 - 10.1097/WNO.0b013e318225247b
DO - 10.1097/WNO.0b013e318225247b
M3 - Review article
C2 - 21734595
AN - SCOPUS:80052271802
VL - 31
SP - 265
EP - 268
JO - Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
JF - Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
SN - 1070-8022
IS - 3
ER -