Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study

Stephen C. Gradwohl; Amrita Aranake; Arbi Ben Abdallah; Paul McNair; Nan Lin; Bradley A. Fritz; Alex Villafranca; David Glick; Eric Jacobsohn; George A. Mashour; Michael S. Avidan

doi:10.1007/s12630-014-0305-8

Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study

Translated title of the contribution: Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study

Stephen C. Gradwohl, Amrita Aranake, Arbi Ben Abdallah, Paul McNair, Nan Lin, Bradley A. Fritz, Alex Villafranca, David Glick, Eric Jacobsohn, George A. Mashour, Michael S. Avidan

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Purpose: The red-hair phenotype, which is often produced by mutations in the melanocortin-1 receptor gene, has been associated with an increase in sedative, anesthetic, and analgesic requirements in both animal and human studies. Nevertheless, the clinical implications of this phenomenon in red-haired patients undergoing surgery are currently unknown.

Translated title of the contribution	Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study
Original language	English
Pages (from-to)	345-355
Number of pages	11
Journal	Canadian Journal of Anesthesia
Volume	62
Issue number	4
DOIs	https://doi.org/10.1007/s12630-014-0305-8
State	Published - Apr 2015

Access to Document

10.1007/s12630-014-0305-8

Cite this

Gradwohl, S. C., Aranake, A., Abdallah, A. B., McNair, P., Lin, N., Fritz, B. A., Villafranca, A., Glick, D., Jacobsohn, E., Mashour, G. A., & Avidan, M. S. (2015). Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study. Canadian Journal of Anesthesia, 62(4), 345-355. https://doi.org/10.1007/s12630-014-0305-8

@article{35c6959e7d204cb59292a03ccac26125,

title = "Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study",

abstract = "Purpose: The red-hair phenotype, which is often produced by mutations in the melanocortin-1 receptor gene, has been associated with an increase in sedative, anesthetic, and analgesic requirements in both animal and human studies. Nevertheless, the clinical implications of this phenomenon in red-haired patients undergoing surgery are currently unknown.",

author = "Gradwohl, {Stephen C.} and Amrita Aranake and Abdallah, {Arbi Ben} and Paul McNair and Nan Lin and Fritz, {Bradley A.} and Alex Villafranca and David Glick and Eric Jacobsohn and Mashour, {George A.} and Avidan, {Michael S.}",

note = "Publisher Copyright: {\textcopyright} 2015, Canadian Anesthesiologists' Society.",

year = "2015",

month = apr,

doi = "10.1007/s12630-014-0305-8",

language = "English",

volume = "62",

pages = "345--355",

journal = "Canadian Journal of Anesthesia",

issn = "0832-610X",

number = "4",

}

Gradwohl, SC, Aranake, A, Abdallah, AB, McNair, P, Lin, N, Fritz, BA, Villafranca, A, Glick, D, Jacobsohn, E, Mashour, GA & Avidan, MS 2015, 'Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study', Canadian Journal of Anesthesia, vol. 62, no. 4, pp. 345-355. https://doi.org/10.1007/s12630-014-0305-8

TY - JOUR

T1 - Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair

T2 - a matched cohort study

AU - Gradwohl, Stephen C.

AU - Aranake, Amrita

AU - Abdallah, Arbi Ben

AU - McNair, Paul

AU - Lin, Nan

AU - Fritz, Bradley A.

AU - Villafranca, Alex

AU - Glick, David

AU - Jacobsohn, Eric

AU - Mashour, George A.

AU - Avidan, Michael S.

PY - 2015/4

Y1 - 2015/4

N2 - Purpose: The red-hair phenotype, which is often produced by mutations in the melanocortin-1 receptor gene, has been associated with an increase in sedative, anesthetic, and analgesic requirements in both animal and human studies. Nevertheless, the clinical implications of this phenomenon in red-haired patients undergoing surgery are currently unknown.

AB - Purpose: The red-hair phenotype, which is often produced by mutations in the melanocortin-1 receptor gene, has been associated with an increase in sedative, anesthetic, and analgesic requirements in both animal and human studies. Nevertheless, the clinical implications of this phenomenon in red-haired patients undergoing surgery are currently unknown.

UR - http://www.scopus.com/inward/record.url?scp=84925481622&partnerID=8YFLogxK

U2 - 10.1007/s12630-014-0305-8

DO - 10.1007/s12630-014-0305-8

M3 - Article

C2 - 25681040

AN - SCOPUS:84925481622

SN - 0832-610X

VL - 62

SP - 345

EP - 355

JO - Canadian Journal of Anesthesia

JF - Canadian Journal of Anesthesia

IS - 4

ER -

Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study

Abstract

Access to Document

Other files and links

Fingerprint

Cite this