Lateral transport of a lipid probe and labeled proteins on a cell membrane

J. Schlessinger; D. Axelrod; D. E. Koppel; W. W. Webb; E. L. Elson

doi:10.1126/science.556653

Lateral transport of a lipid probe and labeled proteins on a cell membrane

J. Schlessinger
, D. Axelrod
, D. E. Koppel
, W. W. Webb
, E. L. Elson

Research output: Contribution to journal › Article › peer-review

183 Scopus citations

Abstract

Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) ∼2 × 10 ^-10 square centimeter per second and D(lipid probe) ∼9 × 10^-9 square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.

Original language	English
Pages (from-to)	307-309
Number of pages	3
Journal	Science
Volume	195
Issue number	4275
DOIs	https://doi.org/10.1126/science.556653
State	Published - 1977

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@article{e6604890d11b4d66a66fe61c9017b034,

title = "Lateral transport of a lipid probe and labeled proteins on a cell membrane",

abstract = "Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) ∼2 × 10 -10 square centimeter per second and D(lipid probe) ∼9 × 10-9 square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.",

author = "J. Schlessinger and D. Axelrod and Koppel, \{D. E.\} and Webb, \{W. W.\} and Elson, \{E. L.\}",

year = "1977",

doi = "10.1126/science.556653",

language = "English",

volume = "195",

pages = "307--309",

journal = "Science",

issn = "0036-8075",

number = "4275",

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TY - JOUR

T1 - Lateral transport of a lipid probe and labeled proteins on a cell membrane

AU - Schlessinger, J.

AU - Axelrod, D.

AU - Koppel, D. E.

AU - Webb, W. W.

AU - Elson, E. L.

PY - 1977

Y1 - 1977

N2 - Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) ∼2 × 10 -10 square centimeter per second and D(lipid probe) ∼9 × 10-9 square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.

AB - Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) ∼2 × 10 -10 square centimeter per second and D(lipid probe) ∼9 × 10-9 square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.

UR - https://www.scopus.com/pages/publications/0017365231

U2 - 10.1126/science.556653

DO - 10.1126/science.556653

M3 - Article

C2 - 556653

AN - SCOPUS:0017365231

SN - 0036-8075

VL - 195

SP - 307

EP - 309

JO - Science

JF - Science

IS - 4275

ER -

Lateral transport of a lipid probe and labeled proteins on a cell membrane

Abstract

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