Lateral transport of a lipid probe and labeled proteins on a cell membrane

J. Schlessinger, D. Axelrod, D. E. Koppel, W. W. Webb, E. L. Elson

Research output: Contribution to journalArticle

164 Scopus citations

Abstract

Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) ∼2 × 10 -10 square centimeter per second and D(lipid probe) ∼9 × 10-9 square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.

Original languageEnglish
Pages (from-to)307-309
Number of pages3
JournalScience
Volume195
Issue number4275
DOIs
StatePublished - Jan 1 1977
Externally publishedYes

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    Schlessinger, J., Axelrod, D., Koppel, D. E., Webb, W. W., & Elson, E. L. (1977). Lateral transport of a lipid probe and labeled proteins on a cell membrane. Science, 195(4275), 307-309. https://doi.org/10.1126/science.556653