Lateral diffusion in planar lipid bilayers

P. F. Fahey; D. E. Koppel; L. S. Barak; D. E. Wolf; E. L. Elson; W. W. Webb

doi:10.1126/science.831279

Lateral diffusion in planar lipid bilayers

P. F. Fahey, D. E. Koppel, L. S. Barak, D. E. Wolf, E. L. Elson, W. W. Webb

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Abstract

Direct measurements by fluorescence correlation spectroscopy of lateral diffusion coefficients of fluorescent lipid analogs in lipid bilayer membranes indicate self-diffusion coefficients D ≳ 10^-7 square centimeters per second for various lipid systems above their reported transition temperatures. Cholesterol in egg lecithin at mole ratio of 1 : 2 reduces D by about twofold, while retained hydrocarbon solvent can increase it by two- to threefold.

Original language	English
Pages (from-to)	305-306
Number of pages	2
Journal	Science
Volume	195
Issue number	4275
DOIs	https://doi.org/10.1126/science.831279
State	Published - 1977

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title = "Lateral diffusion in planar lipid bilayers",

abstract = "Direct measurements by fluorescence correlation spectroscopy of lateral diffusion coefficients of fluorescent lipid analogs in lipid bilayer membranes indicate self-diffusion coefficients D ≳ 10-7 square centimeters per second for various lipid systems above their reported transition temperatures. Cholesterol in egg lecithin at mole ratio of 1 : 2 reduces D by about twofold, while retained hydrocarbon solvent can increase it by two- to threefold.",

author = "Fahey, {P. F.} and Koppel, {D. E.} and Barak, {L. S.} and Wolf, {D. E.} and Elson, {E. L.} and Webb, {W. W.}",

year = "1977",

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AU - Fahey, P. F.

AU - Koppel, D. E.

AU - Barak, L. S.

AU - Wolf, D. E.

AU - Elson, E. L.

AU - Webb, W. W.

PY - 1977

Y1 - 1977

N2 - Direct measurements by fluorescence correlation spectroscopy of lateral diffusion coefficients of fluorescent lipid analogs in lipid bilayer membranes indicate self-diffusion coefficients D ≳ 10-7 square centimeters per second for various lipid systems above their reported transition temperatures. Cholesterol in egg lecithin at mole ratio of 1 : 2 reduces D by about twofold, while retained hydrocarbon solvent can increase it by two- to threefold.

AB - Direct measurements by fluorescence correlation spectroscopy of lateral diffusion coefficients of fluorescent lipid analogs in lipid bilayer membranes indicate self-diffusion coefficients D ≳ 10-7 square centimeters per second for various lipid systems above their reported transition temperatures. Cholesterol in egg lecithin at mole ratio of 1 : 2 reduces D by about twofold, while retained hydrocarbon solvent can increase it by two- to threefold.

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U2 - 10.1126/science.831279

DO - 10.1126/science.831279

M3 - Article

C2 - 831279

AN - SCOPUS:0017350557

SN - 0036-8075

VL - 195

SP - 305

EP - 306

JO - Science

JF - Science

IS - 4275

ER -

Lateral diffusion in planar lipid bilayers

Abstract

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