Lateral Cricoarytenoid Release: Development of a Novel Surgical Treatment Option for Adductor Spasmodic Dysphonia in a Canine Laryngeal Model

Andrea M. Park, Randal C. Paniello

Research output: Contribution to journalArticle

Abstract

Objective: To investigate the efficacy of a novel adductor muscle-releasing technique designed to decrease the force of vocal fold adduction, as a potential surgical therapy for patients with adductor spasmodic dysphonia (ADSD). Study Design: Experimental animal study. Methods: A canine laryngeal model was used to assess the acute and sustained efficacy of a lateral cricoarytenoid (LCA) muscle release. A total of 34 canine hemilaryngeal preparations were divided among 7 experimental groups. The LCA muscle was separated from its cricoid cartilage origin via an open, anterior, submucosal approach. The laryngeal adductory pressures (LAP) were assessed pre- and post-muscle release via direct recurrent laryngeal nerve stimulation. Measurements were repeated at 1.5, 3, or 6 months postoperatively. Another study evaluated release of the thyroarytenoid (TA) muscle from its thyroid cartilage origin. Results: Releasing the LCA muscle demonstrated a significant decrease in LAP acutely and was maintained at all 3 time points with the aid of a barrier (P <.05). Without the barrier, the LCA muscle reattached to the cricoid. Acute release of the TA muscle did not significantly decrease the LAP. Conclusions: The proposed LCA release procedure may provide patients with a permanent treatment option for ADSD. However, longer-term studies and human trials are needed.

Original languageEnglish
Pages (from-to)746-751
Number of pages6
JournalAnnals of Otology, Rhinology and Laryngology
Volume125
Issue number9
DOIs
StatePublished - Sep 1 2016

Keywords

  • adductor spasmodic dysphonia
  • laryngeal disorder
  • lateral cricoarytenoid muscle
  • thyroarytenoid muscle

Fingerprint Dive into the research topics of 'Lateral Cricoarytenoid Release: Development of a Novel Surgical Treatment Option for Adductor Spasmodic Dysphonia in a Canine Laryngeal Model'. Together they form a unique fingerprint.

  • Cite this