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Late endosome motility depends on lipids via the small GTPase Rab7
Cécile Lebrand
, Michela Corti
, Holly Goodson
, Pierre Cosson
,
Valeria Cavalli
, Nathalie Mayran
, Julien Fauré
, Jean Gruenberg
Department of Neuroscience
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Institute of Clinical and Translational Sciences (ICTS)
Center of Regenerative Medicine
DBBS - Molecular Cell Biology
DBBS - Neurosciences
DBBS - Developmental, Regenerative and Stem Cell Biology
DBBS - Biochemistry, Biophysics, and Structural Biology
Hope Center for Neurological Disorders
Bursky Center for Human Immunology & Immunotherapy Programs (CHiiPs)
Research output
:
Contribution to journal
›
Article
›
peer-review
289
Scopus citations
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Keyphrases
Lipids
100%
Motility
100%
Late Endosome
100%
Small GTPase
100%
Rab7
100%
Cholesterol
44%
Overexpression
11%
Motor Function
11%
Control Cell
11%
Paralysis
11%
Endocytic
11%
Membrane-associated
11%
Endocytic Vesicles
11%
Niemann-Pick C
11%
Membrane Lipids
11%
Endocytic Compartment
11%
Kinesin
11%
Cholesterol Accumulation
11%
Dynamic Properties
11%
Cytoplasmic Dynein
11%
Electromembrane Extraction
11%
Guanine nucleotide Dissociation Inhibitor
11%
Biochemistry, Genetics and Molecular Biology
Lipid
100%
Small GTPase
100%
Wild Type
50%
Lipid Composition
50%
Motor Performance
50%
Membrane Lipid
50%
Dynein
50%
Kinesin
50%
Guanine
50%
Neuroscience
GTPase
100%
Kinesin
50%
Membrane Lipid
50%
Cytoplasmic Dynein
50%
Guanine Nucleotide Dissociation Inhibitor
50%
Immunology and Microbiology
Endosome
100%
Wild Type
50%
Motor Performance
50%
Lipid Composition
50%