Laryngeal Mucosal Tumor Mapping with Narrow Band Imaging and Confocal Laser Endomicroscopy

Amanda Atkins; Connor Koch; Sherin James; Akhilesh Wodeyar; Matti Sievert; Miguel Goncalves; Harishanker Jeyarajan; Jason M. Warram; Bharat A. Panuganti

doi:10.1002/lary.31918

Laryngeal Mucosal Tumor Mapping with Narrow Band Imaging and Confocal Laser Endomicroscopy

Amanda Atkins
, Connor Koch
, Sherin James
, Akhilesh Wodeyar
, Matti Sievert
, Miguel Goncalves
, Harishanker Jeyarajan
, Jason M. Warram
, Bharat A. Panuganti

Department of Otolaryngology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Confocal laser endomicroscopy (CLE) represents an emerging probe-based intraoperative optical imaging modality, contingent on differential fluoroscein uptake, equipped to improve intraoperative identification of subclinical mucosal disease. In the analysis herein, we describe improved sensitivity, compared to narrow band imaging and small-volume tissue biopsies, of CLE in the discrimination of occult disease based on cellular and subcellular morphology during endoscopic resection of early-staged larynx cancers. Laryngoscope, 2024.

Original language	English
Pages (from-to)	1767-1770
Number of pages	4
Journal	Laryngoscope
Volume	135
Issue number	5
DOIs	https://doi.org/10.1002/lary.31918
State	Accepted/In press - 2024

Keywords

confocal laser endomicroscopy
early laryngeal cancer
narrow band imaging
tumor mapping

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10.1002/lary.31918

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@article{e82d5fe7379442f7b5f23a32c7f7fe84,

title = "Laryngeal Mucosal Tumor Mapping with Narrow Band Imaging and Confocal Laser Endomicroscopy",

abstract = "Confocal laser endomicroscopy (CLE) represents an emerging probe-based intraoperative optical imaging modality, contingent on differential fluoroscein uptake, equipped to improve intraoperative identification of subclinical mucosal disease. In the analysis herein, we describe improved sensitivity, compared to narrow band imaging and small-volume tissue biopsies, of CLE in the discrimination of occult disease based on cellular and subcellular morphology during endoscopic resection of early-staged larynx cancers. Laryngoscope, 2024.",

keywords = "confocal laser endomicroscopy, early laryngeal cancer, narrow band imaging, tumor mapping",

author = "Amanda Atkins and Connor Koch and Sherin James and Akhilesh Wodeyar and Matti Sievert and Miguel Goncalves and Harishanker Jeyarajan and Warram, \{Jason M.\} and Panuganti, \{Bharat A.\}",

note = "Publisher Copyright: {\textcopyright} 2024 The American Laryngological, Rhinological and Otological Society, Inc.",

year = "2024",

doi = "10.1002/lary.31918",

language = "English",

volume = "135",

pages = "1767--1770",

journal = "Laryngoscope",

issn = "0023-852X",

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T1 - Laryngeal Mucosal Tumor Mapping with Narrow Band Imaging and Confocal Laser Endomicroscopy

AU - Atkins, Amanda

AU - Koch, Connor

AU - James, Sherin

AU - Wodeyar, Akhilesh

AU - Sievert, Matti

AU - Goncalves, Miguel

AU - Jeyarajan, Harishanker

AU - Warram, Jason M.

AU - Panuganti, Bharat A.

PY - 2024

Y1 - 2024

N2 - Confocal laser endomicroscopy (CLE) represents an emerging probe-based intraoperative optical imaging modality, contingent on differential fluoroscein uptake, equipped to improve intraoperative identification of subclinical mucosal disease. In the analysis herein, we describe improved sensitivity, compared to narrow band imaging and small-volume tissue biopsies, of CLE in the discrimination of occult disease based on cellular and subcellular morphology during endoscopic resection of early-staged larynx cancers. Laryngoscope, 2024.

AB - Confocal laser endomicroscopy (CLE) represents an emerging probe-based intraoperative optical imaging modality, contingent on differential fluoroscein uptake, equipped to improve intraoperative identification of subclinical mucosal disease. In the analysis herein, we describe improved sensitivity, compared to narrow band imaging and small-volume tissue biopsies, of CLE in the discrimination of occult disease based on cellular and subcellular morphology during endoscopic resection of early-staged larynx cancers. Laryngoscope, 2024.

KW - confocal laser endomicroscopy

KW - early laryngeal cancer

KW - narrow band imaging

KW - tumor mapping

UR - https://www.scopus.com/pages/publications/85209639189

U2 - 10.1002/lary.31918

DO - 10.1002/lary.31918

M3 - Article

C2 - 39564710

AN - SCOPUS:85209639189

SN - 0023-852X

VL - 135

SP - 1767

EP - 1770

JO - Laryngoscope

JF - Laryngoscope

IS - 5

ER -

Laryngeal Mucosal Tumor Mapping with Narrow Band Imaging and Confocal Laser Endomicroscopy

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Keywords

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